Improved Effector Function of Leukemia-specific T-lymphocyte Clones Trained with AML-derived Dendritic Cells

Recently it was shown that myeloid leukemic cells can be induced to differentiate into leukemia-derived dendritic cells (DC leu ), regaining the stimulatory capacity of professional DCs while presenting the leukemic antigen repertoire. But so far, the induced antileukemic T-cell responses have varie...

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Veröffentlicht in:	Cancer genomics & proteomics 2008-09, Vol.5 (5), p.275-286
Hauptverfasser:	Schuster, Friedhelm R, Buhmann, Raymund, Reuther, Susanne, Hubner, Bernd, Grabrucker, Christine, Liepert, Anja, Reibke, Roland, Lichtner, Peter, Yang, Ting, Kroell, Tanja, Kolb, Hans-Jochem, Borkhardt, Arndt, Schmetzer, Helga
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - immunology Antigens, CD - metabolism Blast Crisis CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism Dendritic Cells - cytology Dendritic Cells - immunology Dendritic Cells - metabolism Flow Cytometry Gene Rearrangement Humans Immunophenotyping Leukemia, Myeloid, Acute - immunology Leukemia, Myeloid, Acute - metabolism Leukemia, Myeloid, Acute - pathology Lymphocyte Activation Receptors, Antigen, T-Cell, alpha-beta - genetics Receptors, Antigen, T-Cell, alpha-beta - metabolism T-Lymphocytes - cytology T-Lymphocytes - immunology T-Lymphocytes - metabolism
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