Evidence for tissue-specific forms of glutaminyl cyclase

Glutaminyl cyclase (QC) is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. An examination of the bovine tissue distribution of QC immunoreactivity, enzyme activity, and mRNA confirmed that QC was abundant in brain and pituitary by all three measures. However, e...

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Veröffentlicht in:	FEBS letters 1999-07, Vol.455 (1), p.159-161
Hauptverfasser:	Sykes, Paul A, Watson, Stephanie J, Temple, Jeffrey S, Bateman, Robert C
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoacyltransferases - genetics Aminoacyltransferases - metabolism Animals Cattle Glutamine Pituitary Gland - enzymology Pyroglutamic acid RNA, Messenger - metabolism Secretory component Spleen Spleen - enzymology Substrate Specificity
Online-Zugang:	Volltext
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