Chamber-specific Regulation of Heme Oxygenase-1 (Heat Shock Protein 32) in Right-sided Congestive Heart Failure

Heme oxygenase (HO)-1 is a stress protein (HSP 32) and, together with HO-2, catalyses oxidation of the heme molecule to generate carbon monoxide, a gas with vasodilatory properties, and bilirubin, an antioxidant. Right-sided heart failure (RHF) resulted in a two-fold increase in the HO-1 transcript...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 1999-08, Vol.31 (8), p.1581-1589
Hauptverfasser:	Raju, Vulapalli S, Imai, Naoaki, Liang, Chang-seng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carbon monoxide production Dogs Gene expression Gene Expression Regulation Heart Failure - enzymology Heart Failure - pathology Heart Ventricles - metabolism Heart Ventricles - pathology Heat shock proteins Heme Oxygenase (Decyclizing) - genetics Heme Oxygenase (Decyclizing) - metabolism Heme Oxygenase-1 Oxidative stress Radioimmunoassay RNA, Messenger - metabolism
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