Inhibition of Vpr-Induced Cell Cycle Abnormality by Quercetin: A Novel Strategy for Searching Compounds Targeting Vpr

Vpr, an accessory gene product of HIV-1 which induces cell cycle abnormality leading to the increased HIV replication, is supposed to be a possible target for anti-AIDS drugs. We recently established a cell line (MIT-23) in which Vpr-induced cell cycle perturbation could be manipulated by a tetracyc...

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