Establishment of the Dorsal-Ventral Axis in Xenopus Embryos Coincides with the Dorsal Enrichment of Dishevelled That Is Dependent on Cortical Rotation

Examination of the subcellular localization of Dishevelled (Dsh) in fertilized Xenopus eggs revealed that Dsh is associated with vesicle-like organelles that are enriched on the prospective dorsal side of the embryo after cortical rotation. Dorsal enrichment of Dsh is blocked by UV irradiation of th...

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Veröffentlicht in:	The Journal of cell biology 1999-07, Vol.146 (2), p.427-437
Hauptverfasser:	Miller, Jeffrey R., Rowning, Brian A., Larabell, Carolyn A., Yang-Snyder, Julia A., Bates, Rebecca L., Moon, Randall T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing Animals Antibodies beta Catenin Biological Transport - drug effects Biological Transport - radiation effects Blastocyst - cytology Blastocyst - metabolism Body Patterning - drug effects Body Patterning - radiation effects Cell Differentiation - drug effects Cell Differentiation - radiation effects Cell Polarity - drug effects Cell Polarity - radiation effects Cells Cellular biology Cytoskeletal Proteins - metabolism Deuterium Oxide - pharmacology Dishevelled Proteins Eggs Embryo, Nonmammalian - drug effects Embryo, Nonmammalian - metabolism Embryo, Nonmammalian - radiation effects Embryogenesis Embryonic Development Embryos Frizzled Receptors Frogs Microtubules Microtubules - drug effects Microtubules - metabolism Models, Biological Natural satellites Nocodazole - pharmacology Oocytes Organelles Organelles - drug effects Organelles - metabolism Phosphoproteins - genetics Phosphoproteins - metabolism Proteins Rats Receptors, G-Protein-Coupled Receptors, Neurotransmitter - genetics Receptors, Neurotransmitter - metabolism Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Rotation Trans-Activators Ultraviolet Rays Xenopus Xenopus laevis - embryology Xenopus laevis - metabolism Xenopus Proteins Zygote - cytology Zygote - drug effects Zygote - metabolism Zygote - radiation effects
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