Preparation and characterization of protein C-loaded PLA nanoparticles

This paper deals with the preparation and the characterization of poly(lactic acid) (PLA) nanoparticles containing protein C, a plasma inhibitor. Nanoparticles were prepared by the double emulsion method (w/o/w), using methylene chloride as an organic solvent and polyvinyl alcohol (PVA) or human ser...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of controlled release 1999-08, Vol.60 (2-3), p.179-188
Hauptverfasser:	Zambaux, M.F., Bonneaux, F., Gref, R., Dellacherie, E., Vigneron, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticoagulants - chemistry Biodegradable nanoparticles Biological and medical sciences Delayed-Action Preparations - pharmacokinetics Drug Stability General pharmacology Humans In Vitro Techniques Lactic Acid - chemistry Medical sciences Methylene Chloride - chemistry Microspheres Particle Size Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Poly(lactic acid) Polymers - chemistry Polyvinyl Alcohol - chemistry Protein C Protein C - chemistry Protein delivery Protein stability Sonication Surface-Active Agents - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!