A screen of candidates from peaks of linkage: evidence for the involvement of myeloperoxidase in multiple sclerosis

We tested 11 microsatellite markers for evidence of transmission distortion in 744 trio families with multiple sclerosis. Ten of the markers lie within or near to candidate genes selected on the basis that they map within the regions of potential linkage identified in our previously reported linkage...

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Veröffentlicht in:	Journal of neuroimmunology 1999-08, Vol.98 (2), p.208-213
Hauptverfasser:	Chataway, Jeremy, Sawcer, Stephen, Feakes, Robert, Coraddu, Francesca, Broadley, Simon, Jones, Hywel B, Clayton, David, Gray, Julia, Goodfellow, Peter N, Compston, Alastair
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Disease Susceptibility DNA Primers DNA, Satellite - analysis Female Genetic Linkage Genetic Markers Genetic Testing Genome screen Humans Male Multiple sclerosis Multiple Sclerosis - diagnosis Multiple Sclerosis - enzymology Multiple Sclerosis - genetics myeloperoxidase Myeloperoxidase gene Peroxidase - genetics Peroxidase - immunology Polymerase Chain Reaction Polymorphism, Genetic
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