1,25‐Dihydroxyvitamin D3 Regulates the Synthesis of γ‐Glutamyl Transpeptidase and Glutathione Levels in Rat Primary Astrocytes

: Astrocytes play a pivotal role in CNS detoxification pathways, where glutathione (GSH) is involved in the elimination of oxygen and nitrogen reactive species such as nitric oxide. We have previously demonstrated that the specific activity of γ‐glutamyl transpeptidase (γ‐GT), an enzyme of central s...

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Veröffentlicht in:	Journal of neurochemistry 1999-08, Vol.73 (2), p.859-866
Hauptverfasser:	Garcion, E., Sindji, L., Leblondel, G., Brachet, P., Darcy, F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes Astrocytes - cytology Astrocytes - drug effects Astrocytes - enzymology Biological and medical sciences Blotting, Northern Brain inflammation Calcitriol - pharmacology Calcium Channel Agonists - pharmacology Cells, Cultured Encephalitis - enzymology Fundamental and applied biological sciences. Psychology gamma-Glutamyltransferase - biosynthesis Glutathione Glutathione - metabolism Isolated neuron and nerve. Neuroglia Lipopolysaccharides - pharmacology Nitric oxide Nitrites - metabolism Nitrogen - metabolism Rats RNA, Messenger - metabolism Vertebrates: nervous system and sense organs Vitamin D Vitamin D - metabolism γ‐Glutamyl transpeptidase
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