Anxiolytic and antidepressant characteristics of impaza

Antibodies to endothelial NO synthase in ultralow doses exhibited anxiolytic and antidepressant effects and their efficiency after single and course treatment is not inferior to that of amitriptyline and diazepam. The psychotropic activity of ultralow-dose antibodies to endothelial NO-synthase is pr...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2008-06, Vol.145 (6), p.735-737
Hauptverfasser:	Voronina, T. A., Molodavkin, G. M., Zhavbert, E. S., Tarasov, S. A., Kheyfets, I. A., Dugina, J. L., Sergeeva, S. A., Epstein, O. I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amitriptyline - pharmacology Amitriptyline - therapeutic use Animals Anti-Anxiety Agents - pharmacology Anti-Anxiety Agents - therapeutic use Antibodies - immunology Antibodies - pharmacology Antibodies - therapeutic use Antidepressive Agents - pharmacology Antidepressive Agents - therapeutic use Biomedical and Life Sciences Biomedicine Cell Biology Depression - prevention & control Depression - psychology Diazepam - pharmacology Diazepam - therapeutic use Internal Medicine Laboratory Medicine Male Maze Learning - drug effects Nitric Oxide Synthase Type III - immunology Pathology Rats Stress, Psychological - prevention & control Stress, Psychological - psychology Swimming - psychology
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Zusammenfassung:	Antibodies to endothelial NO synthase in ultralow doses exhibited anxiolytic and antidepressant effects and their efficiency after single and course treatment is not inferior to that of amitriptyline and diazepam. The psychotropic activity of ultralow-dose antibodies to endothelial NO-synthase is presumably one of important mechanisms of their efficiency in the treatment of erectile dysfunction.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-008-0193-4