The significance of angiogenic growth factor in the pathogenesis of gestosis in pregnant women with varicose disease
Recently, a close relationship between angiogenesis processes, growth factor activity in vascular abnormalities, and gestosis was revealed. In the present study, the dynamics of serum vascular endothelial growth factor during pregnancy was studied in patients with varicose disease with and without g...
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| Veröffentlicht in: | Bulletin of experimental biology and medicine 2008-04, Vol.145 (4), p.480-482 |
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| container_title | Bulletin of experimental biology and medicine |
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| creator | Sokolyan, A. V. Murashko, A. V. Krechetova, L. V. Ziganshina, M. M. Sukhikh, G. T. |
| description | Recently, a close relationship between angiogenesis processes, growth factor activity in vascular abnormalities, and gestosis was revealed. In the present study, the dynamics of serum vascular endothelial growth factor during pregnancy was studied in patients with varicose disease with and without gestosis and in healthy women. The level of vascular endothelial growth factor increased during normal pregnancy, but decreased in gestosis. In pregnant patients with varicose disease, a less pronounced increase in this parameter was observed in comparison with that in healthy women. |
| doi_str_mv | 10.1007/s10517-008-0123-5 |
| format | Article |
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| subjects | Biomedical and Life Sciences Biomedicine Case-Control Studies Cell Biology Female Gestational Age Humans Internal Medicine Laboratory Medicine Pathology Pre-Eclampsia - blood Pregnancy Pregnancy Complications, Cardiovascular - blood Varicose Veins - blood Varicose Veins - complications Vascular Endothelial Growth Factor A - blood Vascular Endothelial Growth Factor A - physiology |
| title | The significance of angiogenic growth factor in the pathogenesis of gestosis in pregnant women with varicose disease |
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