Syringolymphoid hyperplasia and follicular mucinosis in a patient with cutaneous T-cell lymphoma

Syringolymphoid hyperplasia with alopecia is an uncommon chronic dermatosis of which 9 cases have been reported, with or without follicular mucinosis or cutaneous T-cell lymphoma. We report a patient with cutaneous T-cell lymphoma and syringolymphoid hyperplasia and follicular mucinosis and review t...

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Veröffentlicht in:Journal of the American Academy of Dermatology 1999-08, Vol.41 (2), p.303-308
Hauptverfasser: Tannous, Zeina, Baldassano, Marisa F., Li, Vincent W., Kvedar, Joseph, Duncan, Lyn M.
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container_end_page 308
container_issue 2
container_start_page 303
container_title Journal of the American Academy of Dermatology
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creator Tannous, Zeina
Baldassano, Marisa F.
Li, Vincent W.
Kvedar, Joseph
Duncan, Lyn M.
description Syringolymphoid hyperplasia with alopecia is an uncommon chronic dermatosis of which 9 cases have been reported, with or without follicular mucinosis or cutaneous T-cell lymphoma. We report a patient with cutaneous T-cell lymphoma and syringolymphoid hyperplasia and follicular mucinosis and review the previously reported cases. All reported cases with syringolymphoid hyperplasia were men (10 of 10), with the clinical findings of alopecia (9 of 10) and anhidrosis (3 of 10). Only 3 of 10 cases had associated follicular mucinosis. Of the 7 cases investigated, 6 were found to hve cutaneous T-cell lymphoma. Three patients were not investigated for cutaneous T-cell lymphoma. Although syringolymphoid hyperplasia can be idiopathic, it can also reflect a syringotropic cutaneous T-cell lymphoma. Careful follow-up with a biopsy of persistent lesions is recommended to evaluate for the presence of lymphoma. (J Am Acad Dermatol 1999;41:303-8.)
doi_str_mv 10.1016/S0190-9622(99)70370-1
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We report a patient with cutaneous T-cell lymphoma and syringolymphoid hyperplasia and follicular mucinosis and review the previously reported cases. All reported cases with syringolymphoid hyperplasia were men (10 of 10), with the clinical findings of alopecia (9 of 10) and anhidrosis (3 of 10). Only 3 of 10 cases had associated follicular mucinosis. Of the 7 cases investigated, 6 were found to hve cutaneous T-cell lymphoma. Three patients were not investigated for cutaneous T-cell lymphoma. Although syringolymphoid hyperplasia can be idiopathic, it can also reflect a syringotropic cutaneous T-cell lymphoma. Careful follow-up with a biopsy of persistent lesions is recommended to evaluate for the presence of lymphoma. 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subjects Aged
Biological and medical sciences
Biopsy
Dermatology
Eccrine Glands - pathology
Humans
Hyperplasia
Lymphoma, T-Cell, Cutaneous - complications
Lymphoma, T-Cell, Cutaneous - diagnosis
Lymphoma, T-Cell, Cutaneous - pathology
Male
Medical sciences
Mucinosis, Follicular - complications
Mucinosis, Follicular - pathology
Skin - pathology
Skin Neoplasms - complications
Skin Neoplasms - diagnosis
Skin Neoplasms - pathology
Tumors of the skin and soft tissue. Premalignant lesions
title Syringolymphoid hyperplasia and follicular mucinosis in a patient with cutaneous T-cell lymphoma
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