Simple and rapid high-performance liquid chromatography analysis of propentofylline and its main metabolites in serum using a direct injection technique

A rapid, simple and reliable high‐performance liquid chromatography (HPLC) column‐switching method with UV detection (270 nm) for the simultaneous determination of propentofylline and its metabolites in human and rat sera was developed. The method involves direct injection of serum onto an HPLC colu...

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Veröffentlicht in:	Biomedical chromatography 1999-08, Vol.13 (5), p.340-343
Hauptverfasser:	Kuroda, Naotaka, Hamachi, Yozo, Aoki, Noriko, Wada, Mitsuhiro, Tanigawa, Mihoko, Nakashima, Kenichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromatography, High Pressure Liquid Humans Hydrogen-Ion Concentration Indicators and Reagents Neuroprotective Agents - analysis Neuroprotective Agents - blood Neuroprotective Agents - pharmacokinetics Rats Spectrophotometry, Ultraviolet Xanthines - analysis Xanthines - blood Xanthines - pharmacokinetics
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