Calmodulin, gametes and fertilisation

The role of calmodulin in fertilisation events was examined in a zona-free mouse system by using a selective calmodulin inhibitor, calmidazolium (1 μM). The effects of this antagonist were studied either on the ooplasmic calcium oscillations induced by fertilisation by using the Ca2+ indicator, fluo...

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Veröffentlicht in:	Zygote (Cambridge) 1999-05, Vol.7 (2), p.95-104
Hauptverfasser:	Courtot, Anne-Marie, Pesty, Arlette, Lefèvre, Brigitte
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrosome Reaction - drug effects Animals Calcium - metabolism Calcium Signaling Calmidazolium Calmodulin - antagonists & inhibitors Calmodulin - physiology Cell Nucleus - physiology Confocal imaging Enzyme Inhibitors - pharmacology Female Fertilisation Fertilization in Vitro Imidazoles - pharmacology Male Mice Mice, Inbred C57BL Mice, Inbred CBA Microscopy, Confocal Mouse Oocytes - physiology Sperm-Ovum Interactions Spermatozoa Spermatozoa - drug effects Spermatozoa - physiology
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