Ethanol-reinforced behaviour in the rat: effects of naltrexone

It has been repeatedly reported that endogenous opioid pathways play an important role in ethanol drinking behaviour. In line with these findings, a non-selective opioid receptor antagonist, naltrexone, seems to reduce relapse rates in detoxified alcoholics. The aim of the present study was to evalu...

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Veröffentlicht in:	European journal of pharmacology 1999-06, Vol.374 (3), p.321-327
Hauptverfasser:	Bienkowski, Przemyslaw, Kostowski, Wojciech, Koros, Eliza
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Drinking - psychology Alcoholism and acute alcohol poisoning Analysis of Variance Animals Behavior, Animal - drug effects Behavior, Animal - physiology Biological and medical sciences Central Nervous System Depressants - pharmacology Conditioning, Operant - physiology Ethanol - pharmacology Ethanol self-administration Extinction Extinction, Psychological - drug effects Male Medical sciences Naltrexone Naltrexone - pharmacology Narcotic Antagonists - pharmacology Opioid receptor Rat Rats Rats, Wistar Reinforcement (Psychology) Reinstatement Relapse Self Administration Toxicology Water - pharmacology
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