Establishment of a quiescent herpes simplex virus type 1 infection in neurally-differentiated PC12 cells

Rat pheochromocytoma (PC12) cells differentiated with nerve growth factor (Nd-PC12) were used to investigate the establishment of a non-productive herpes simplex virus type 1 (HSV-1) infection that is reversible. The results of this work are as follows: (i) Nd-PC12 cultures could be maintained as lo...

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Veröffentlicht in:	Journal of neurovirology 1999-06, Vol.5 (3), p.258-267
Hauptverfasser:	Danaher, Robert J, Jacob, Robert J, Miller, Craig S
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyclovir - pharmacology Animals Antiviral Agents - pharmacology Biological and medical sciences Blotting, Southern Cell Count Cell Culture Techniques - methods Cercopithecus aethiops Colforsin - pharmacology Culture Media - chemistry DNA Primers - genetics DNA, Complementary - analysis Gene Expression Regulation, Viral Herpes simplex virus 1 Herpesvirus 1, Human - genetics Herpesvirus 1, Human - isolation & purification Herpesvirus 1, Human - physiology Human viral diseases Infectious diseases Medical sciences PC12 Cells - cytology PC12 Cells - virology Polymerase Chain Reaction Rats Vero Cells Viral diseases Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye Virus Activation Virus Latency - drug effects Virus Latency - physiology
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