High-dose methylprednisolone is effective in the management of acute graft-versus-host disease in severe combined immune deficiency

To the Editor: Severe combined immune deficiency (SCID) is a heterogeneous group of inherited diseases characterized by significantly impaired immunity leading to death in infancy unless treated with bone marrow transplantation (BMT).1 When successful, BMT provides full immune reconstitution and lon...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2008-12, Vol.122 (6), p.1215-1216
Hauptverfasser:	Somech, Raz, MD, Kavadas, Fotini D., MD, Atkinson, Adelle, MD, Grunebaum, Eyal, MD, Roifman, Chaim M., MD, FRCPC
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Age Allergy and Immunology Anti-Inflammatory Agents - administration & dosage Blood pressure Bone marrow Bone Marrow Transplantation Disease-Free Survival Female Graft vs Host Disease - drug therapy Graft vs Host Disease - genetics Graft vs Host Disease - mortality Humans Infant Infant, Newborn Male Medical treatment Methylprednisolone - administration & dosage Patients Retrospective Studies Severe Combined Immunodeficiency - genetics Severe Combined Immunodeficiency - mortality Severe Combined Immunodeficiency - therapy Transplants & implants
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