In vitro characterization and preferential infection by canine distemper virus of glial precursors with Schwann cell characteristics from adult canine brain

Aims: Canine distemper virus (CDV)‐induced demyelinating leukoencephalomyelitis is a naturally occurring model for multiple sclerosis. The aim of this study was to establish primary glial cell cultures from adult canine brain for the analysis of CDV spread and cell tropism. Methods: Cultures were in...

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Veröffentlicht in:	Neuropathology and applied neurobiology 2008-12, Vol.34 (6), p.621-637
Hauptverfasser:	Orlando, E. A., Imbschweiler, I., Gerhauser, I., Baumgärtner, W., Wewetzer, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	aldynoglia Animals Biological and medical sciences Brain - cytology Brain - virology Canine distemper virus Cell Differentiation Cell Proliferation Cells, Cultured Cytopathogenic Effect, Viral Distemper Virus, Canine - genetics Distemper Virus, Canine - physiology Dogs Fluorescent Antibody Technique Medical sciences Microscopy, Fluorescence Neuroglia - cytology Neuroglia - physiology Neuroglia - virology Neurology p75NTR precursor remyelination Schwann Cells - cytology Schwann Cells - physiology Schwann Cells - virology Stem Cells - cytology Stem Cells - physiology Stem Cells - virology Vascular diseases and vascular malformations of the nervous system
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