Construction of GSK-3beta-targeting RNAi adenovirus vector and the influence of Wnt/beta-catenin pathway in proliferation of human thyrocytes

To construct RNAi recombinant adenoviral expressive vectors specific to glycogen synthase kinase-3beta (GSK-3beta) and to observe its gene knockdown effect on the expression of GSK-3beta, and to explore the effect of Wnt/beta-catenin pathway on the proliferation of human thyrocytes using the RNAi ad...

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Veröffentlicht in:	Zhong hua yi xue za zhi 2008-11, Vol.88 (40), p.2821-2825
Hauptverfasser:	Chen, Gang, Mou, Lun-pan, Yao, Jin, You, Ting-ting, Shen, Xiao-yan, Zhu, Xiang-qing, Qiao, Yu-fang, Lin, Miao, Fang, Xiao-wen, Zou, Xin, Lin, Li-xiang
Format:	Artikel
Sprache:	chi
Schlagworte:	Adenoviridae beta Catenin - metabolism Cell Line Cell Proliferation Genetic Vectors Glycogen Synthase Kinase 3 - genetics Humans RNA Interference Thyroid Gland - cytology Wnt Proteins - metabolism
Online-Zugang:	Volltext
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