Dissecting Signaling Pathways That Govern Self-renewal of Rabbit Embryonic Stem Cells

The pluripotency and self-renewal of embryonic stem cells (ESC) are regulated by a variety of cytokines/growth factors with some species differences. We reported previously that rabbit ESC (rESC) are more similar to primate ESC than to mouse ESC. However, the signaling pathways that regulate rESC se...

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Veröffentlicht in:	The Journal of biological chemistry 2008-12, Vol.283 (51), p.35929-35940
Hauptverfasser:	Wang, Shufen, Shen, Yi, Yuan, Xiaohua, Chen, Kai, Guo, Xiangyu, Chen, Yongchang, Niu, Yuyu, Li, Jian, Xu, Ren-He, Yan, Xiyun, Zhou, Qi, Ji, Weizhi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals beta Catenin - metabolism Carrier Proteins - metabolism Cell Differentiation - drug effects Cell Differentiation - physiology Cell Line Cell Proliferation - drug effects Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Epidermal Growth Factor - metabolism Epidermal Growth Factor - pharmacology MAP Kinase Signaling System - drug effects MAP Kinase Signaling System - physiology Mitogen-Activated Protein Kinase 1 - metabolism Mitogen-Activated Protein Kinase 3 - metabolism Phosphatidylinositol 3-Kinases - metabolism Phosphorylation - drug effects Phosphorylation - physiology Pluripotent Stem Cells - cytology Pluripotent Stem Cells - metabolism Proto-Oncogene Proteins c-akt - metabolism Rabbits Smad2 Protein - metabolism Smad3 Protein - metabolism Transforming Growth Factor beta - metabolism Transforming Growth Factor beta - pharmacology Wnt Proteins - metabolism
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