Androgens Promote Oocyte Insulin-Like Growth Factor I Expression and Initiation of Follicle Development in the Primate Ovary

In the study reported here, we investigated the effect of androgens on recruitment of resting, primordial follicles into the actively growing pool. Healthy, random-cycling female rhesus monkeys were treated with testosterone, dihydrotestosterone (DHT), or vehicle for 3â10 days, after which ovaries...

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Veröffentlicht in:	Biology of reproduction 1999-08, Vol.61 (2), p.353-357
Hauptverfasser:	VENDOLA, K, JIAN ZHOU, JIE WANG, FAMUYIWA, O. A, BIEVRE, M, BONDY, C. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens - pharmacology Animals Biological and medical sciences Dihydrotestosterone - pharmacology Female Fundamental and applied biological sciences. Psychology Hormone metabolism and regulation Insulin-Like Growth Factor I - biosynthesis Insulin-Like Growth Factor I - genetics Macaca mulatta Macaca mulatta - growth & development Mammalian female genital system Oocytes - drug effects Oocytes - metabolism Ovarian Follicle - growth & development Receptor, IGF Type 1 - biosynthesis Receptor, IGF Type 1 - genetics RNA, Messenger - analysis Testosterone - pharmacology Vertebrates: reproduction
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