Effect of calcitriol and pamidronate in multiple myeloma

Addition of bisphosphonates to standard treatment of multiple myeloma (MM) decreases bone pain and skeletal events without influencing bone healing. Calcitriol, besides its established effects on bone remodeling and calcium metabolism, has both immunoregulatory and cell differentiating effects in vi...

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Veröffentlicht in:	The American journal of the medical sciences 1999-07, Vol.318 (1), p.61-66
Hauptverfasser:	IMSEIS, R. E, PALMIERI, G. M. A, HOLBERT, J. M, LEVENTHAL, M. R, SEBES, J. I
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - therapeutic use Biological and medical sciences Bone Density - drug effects Bone Remodeling - drug effects Bones, joints and connective tissue. Antiinflammatory agents Calcitriol - blood Calcitriol - therapeutic use Calcium Channel Agonists - blood Calcium Channel Agonists - therapeutic use Diphosphonates - therapeutic use Female Humans Male Medical sciences Middle Aged Multiple Myeloma - blood Multiple Myeloma - drug therapy Pamidronate Pharmacology. Drug treatments
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