Comparison of Ultrafiltration, Nesiritide, and Usual Care in Acute Decompensated Heart Failure

To study the short‐term effects of initial treatment strategies for acute decompensated heart failure, 25 patients treated with ultrafiltration (UF) were retrospectively compared with 25 patients treated with usual care (UC) and 25 patients treated with UC plus adjunctive nesiritide infusion (UN), m...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Congestive heart failure (Greenwich, Conn.) Conn.), 2008-11, Vol.14 (6), p.298-301
Hauptverfasser: Bartone, Cheryl, Saghir, Syed, Menon, Santosh G., Brosmer, Jayna, Kereiakes, Dean J., Mazur, Wojciech, Chung, Eugene S.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 301
container_issue 6
container_start_page 298
container_title Congestive heart failure (Greenwich, Conn.)
container_volume 14
creator Bartone, Cheryl
Saghir, Syed
Menon, Santosh G.
Brosmer, Jayna
Kereiakes, Dean J.
Mazur, Wojciech
Chung, Eugene S.
description To study the short‐term effects of initial treatment strategies for acute decompensated heart failure, 25 patients treated with ultrafiltration (UF) were retrospectively compared with 25 patients treated with usual care (UC) and 25 patients treated with UC plus adjunctive nesiritide infusion (UN), matched for age, sex, ejection fraction, etiology, and serum creatinine. The median length of hospitalization was 6 days for UF, 4 days for UC, and 6 days for UN. All‐cause 30‐day readmissions tended to be fewer in the UF (16%) compared with the UN (24%) or UC (24%) groups. All groups lost weight, although to a greater extent in the UF group (15.8 lb vs 6.3 lb in UC and 4.7 lb in UN). Concomitantly, UF manifested the greatest increase in serum urea nitrogen, creatinine, and the number of patients with creatinine increases of >0.5 mg/dL (44% vs 24% in UC and 20% in UN). In acute decompensated heart failure, UF appears to be more effective for volume removal and possibly prevention of all‐cause hospital readmission to 30 days than UC or UN. These findings, as well as the effects on renal function and length of stay, need to be further evaluated in a prospective randomized study.
doi_str_mv 10.1111/j.1751-7133.2008.00020.x
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69891816</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69891816</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3970-230d7a806dd3b6b156811fab81a6f527299bd810554d30c6b5a88de5f46ce2783</originalsourceid><addsrcrecordid>eNqNkMFOwzAMhiMEYmPwCignTmtJmiVNJS5TYQxpggu7EqWNK2Xq2pG0Ynt7UjbBFR9sS_79W_4QwpTENMT9JqYpp1FKGYsTQmRMCElIvD9D49_Beeh5kkY8ybIRuvJ-QwhnTGaXaEQzkgrJ6Rh95O12p531bYPbCq_rzunKDrmzbTPFr-Cts501MMW6MXjte13jXDvAtsHzsu8AP0IZTKDxugODl6Bdhxfa1r2Da3RR6drDzalO0Hrx9J4vo9Xb80s-X0Uly1ISJYyYVEsijGGFKCgXktJKF5JqUYUnwguFkZRwPjOMlKLgWkoDvJqJEpJUsgm6O_ruXPvZg-_U1voS6lo30PZeiUxmVFIRhPIoLF3rvYNK7ZzdandQlKiBrdqoAaEaEKqBrfphq_Zh9fZ0oy-2YP4WTzCD4OEo-LI1HP5trPLlIjTsG22dhwc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69891816</pqid></control><display><type>article</type><title>Comparison of Ultrafiltration, Nesiritide, and Usual Care in Acute Decompensated Heart Failure</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Access via Wiley Online Library</source><creator>Bartone, Cheryl ; Saghir, Syed ; Menon, Santosh G. ; Brosmer, Jayna ; Kereiakes, Dean J. ; Mazur, Wojciech ; Chung, Eugene S.</creator><creatorcontrib>Bartone, Cheryl ; Saghir, Syed ; Menon, Santosh G. ; Brosmer, Jayna ; Kereiakes, Dean J. ; Mazur, Wojciech ; Chung, Eugene S.</creatorcontrib><description>To study the short‐term effects of initial treatment strategies for acute decompensated heart failure, 25 patients treated with ultrafiltration (UF) were retrospectively compared with 25 patients treated with usual care (UC) and 25 patients treated with UC plus adjunctive nesiritide infusion (UN), matched for age, sex, ejection fraction, etiology, and serum creatinine. The median length of hospitalization was 6 days for UF, 4 days for UC, and 6 days for UN. All‐cause 30‐day readmissions tended to be fewer in the UF (16%) compared with the UN (24%) or UC (24%) groups. All groups lost weight, although to a greater extent in the UF group (15.8 lb vs 6.3 lb in UC and 4.7 lb in UN). Concomitantly, UF manifested the greatest increase in serum urea nitrogen, creatinine, and the number of patients with creatinine increases of &gt;0.5 mg/dL (44% vs 24% in UC and 20% in UN). In acute decompensated heart failure, UF appears to be more effective for volume removal and possibly prevention of all‐cause hospital readmission to 30 days than UC or UN. These findings, as well as the effects on renal function and length of stay, need to be further evaluated in a prospective randomized study.</description><identifier>ISSN: 1527-5299</identifier><identifier>EISSN: 1751-7133</identifier><identifier>DOI: 10.1111/j.1751-7133.2008.00020.x</identifier><identifier>PMID: 19076851</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Aged ; Blood Urea Nitrogen ; Creatinine - blood ; Female ; Heart Failure - blood ; Heart Failure - drug therapy ; Heart Failure - physiopathology ; Heart Failure - therapy ; Humans ; Length of Stay ; Male ; Natriuretic Agents - therapeutic use ; Natriuretic Peptide, Brain - therapeutic use ; Retrospective Studies ; Stroke Volume ; Ultrafiltration</subject><ispartof>Congestive heart failure (Greenwich, Conn.), 2008-11, Vol.14 (6), p.298-301</ispartof><rights>2008 Le Jacq</rights><rights>(c) 2008 Le Jacq</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3970-230d7a806dd3b6b156811fab81a6f527299bd810554d30c6b5a88de5f46ce2783</citedby><cites>FETCH-LOGICAL-c3970-230d7a806dd3b6b156811fab81a6f527299bd810554d30c6b5a88de5f46ce2783</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1751-7133.2008.00020.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1751-7133.2008.00020.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19076851$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bartone, Cheryl</creatorcontrib><creatorcontrib>Saghir, Syed</creatorcontrib><creatorcontrib>Menon, Santosh G.</creatorcontrib><creatorcontrib>Brosmer, Jayna</creatorcontrib><creatorcontrib>Kereiakes, Dean J.</creatorcontrib><creatorcontrib>Mazur, Wojciech</creatorcontrib><creatorcontrib>Chung, Eugene S.</creatorcontrib><title>Comparison of Ultrafiltration, Nesiritide, and Usual Care in Acute Decompensated Heart Failure</title><title>Congestive heart failure (Greenwich, Conn.)</title><addtitle>Congest Heart Fail</addtitle><description>To study the short‐term effects of initial treatment strategies for acute decompensated heart failure, 25 patients treated with ultrafiltration (UF) were retrospectively compared with 25 patients treated with usual care (UC) and 25 patients treated with UC plus adjunctive nesiritide infusion (UN), matched for age, sex, ejection fraction, etiology, and serum creatinine. The median length of hospitalization was 6 days for UF, 4 days for UC, and 6 days for UN. All‐cause 30‐day readmissions tended to be fewer in the UF (16%) compared with the UN (24%) or UC (24%) groups. All groups lost weight, although to a greater extent in the UF group (15.8 lb vs 6.3 lb in UC and 4.7 lb in UN). Concomitantly, UF manifested the greatest increase in serum urea nitrogen, creatinine, and the number of patients with creatinine increases of &gt;0.5 mg/dL (44% vs 24% in UC and 20% in UN). In acute decompensated heart failure, UF appears to be more effective for volume removal and possibly prevention of all‐cause hospital readmission to 30 days than UC or UN. These findings, as well as the effects on renal function and length of stay, need to be further evaluated in a prospective randomized study.</description><subject>Aged</subject><subject>Blood Urea Nitrogen</subject><subject>Creatinine - blood</subject><subject>Female</subject><subject>Heart Failure - blood</subject><subject>Heart Failure - drug therapy</subject><subject>Heart Failure - physiopathology</subject><subject>Heart Failure - therapy</subject><subject>Humans</subject><subject>Length of Stay</subject><subject>Male</subject><subject>Natriuretic Agents - therapeutic use</subject><subject>Natriuretic Peptide, Brain - therapeutic use</subject><subject>Retrospective Studies</subject><subject>Stroke Volume</subject><subject>Ultrafiltration</subject><issn>1527-5299</issn><issn>1751-7133</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMFOwzAMhiMEYmPwCignTmtJmiVNJS5TYQxpggu7EqWNK2Xq2pG0Ynt7UjbBFR9sS_79W_4QwpTENMT9JqYpp1FKGYsTQmRMCElIvD9D49_Beeh5kkY8ybIRuvJ-QwhnTGaXaEQzkgrJ6Rh95O12p531bYPbCq_rzunKDrmzbTPFr-Cts501MMW6MXjte13jXDvAtsHzsu8AP0IZTKDxugODl6Bdhxfa1r2Da3RR6drDzalO0Hrx9J4vo9Xb80s-X0Uly1ISJYyYVEsijGGFKCgXktJKF5JqUYUnwguFkZRwPjOMlKLgWkoDvJqJEpJUsgm6O_ruXPvZg-_U1voS6lo30PZeiUxmVFIRhPIoLF3rvYNK7ZzdandQlKiBrdqoAaEaEKqBrfphq_Zh9fZ0oy-2YP4WTzCD4OEo-LI1HP5trPLlIjTsG22dhwc</recordid><startdate>200811</startdate><enddate>200811</enddate><creator>Bartone, Cheryl</creator><creator>Saghir, Syed</creator><creator>Menon, Santosh G.</creator><creator>Brosmer, Jayna</creator><creator>Kereiakes, Dean J.</creator><creator>Mazur, Wojciech</creator><creator>Chung, Eugene S.</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200811</creationdate><title>Comparison of Ultrafiltration, Nesiritide, and Usual Care in Acute Decompensated Heart Failure</title><author>Bartone, Cheryl ; Saghir, Syed ; Menon, Santosh G. ; Brosmer, Jayna ; Kereiakes, Dean J. ; Mazur, Wojciech ; Chung, Eugene S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3970-230d7a806dd3b6b156811fab81a6f527299bd810554d30c6b5a88de5f46ce2783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Aged</topic><topic>Blood Urea Nitrogen</topic><topic>Creatinine - blood</topic><topic>Female</topic><topic>Heart Failure - blood</topic><topic>Heart Failure - drug therapy</topic><topic>Heart Failure - physiopathology</topic><topic>Heart Failure - therapy</topic><topic>Humans</topic><topic>Length of Stay</topic><topic>Male</topic><topic>Natriuretic Agents - therapeutic use</topic><topic>Natriuretic Peptide, Brain - therapeutic use</topic><topic>Retrospective Studies</topic><topic>Stroke Volume</topic><topic>Ultrafiltration</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bartone, Cheryl</creatorcontrib><creatorcontrib>Saghir, Syed</creatorcontrib><creatorcontrib>Menon, Santosh G.</creatorcontrib><creatorcontrib>Brosmer, Jayna</creatorcontrib><creatorcontrib>Kereiakes, Dean J.</creatorcontrib><creatorcontrib>Mazur, Wojciech</creatorcontrib><creatorcontrib>Chung, Eugene S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Congestive heart failure (Greenwich, Conn.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bartone, Cheryl</au><au>Saghir, Syed</au><au>Menon, Santosh G.</au><au>Brosmer, Jayna</au><au>Kereiakes, Dean J.</au><au>Mazur, Wojciech</au><au>Chung, Eugene S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of Ultrafiltration, Nesiritide, and Usual Care in Acute Decompensated Heart Failure</atitle><jtitle>Congestive heart failure (Greenwich, Conn.)</jtitle><addtitle>Congest Heart Fail</addtitle><date>2008-11</date><risdate>2008</risdate><volume>14</volume><issue>6</issue><spage>298</spage><epage>301</epage><pages>298-301</pages><issn>1527-5299</issn><eissn>1751-7133</eissn><abstract>To study the short‐term effects of initial treatment strategies for acute decompensated heart failure, 25 patients treated with ultrafiltration (UF) were retrospectively compared with 25 patients treated with usual care (UC) and 25 patients treated with UC plus adjunctive nesiritide infusion (UN), matched for age, sex, ejection fraction, etiology, and serum creatinine. The median length of hospitalization was 6 days for UF, 4 days for UC, and 6 days for UN. All‐cause 30‐day readmissions tended to be fewer in the UF (16%) compared with the UN (24%) or UC (24%) groups. All groups lost weight, although to a greater extent in the UF group (15.8 lb vs 6.3 lb in UC and 4.7 lb in UN). Concomitantly, UF manifested the greatest increase in serum urea nitrogen, creatinine, and the number of patients with creatinine increases of &gt;0.5 mg/dL (44% vs 24% in UC and 20% in UN). In acute decompensated heart failure, UF appears to be more effective for volume removal and possibly prevention of all‐cause hospital readmission to 30 days than UC or UN. These findings, as well as the effects on renal function and length of stay, need to be further evaluated in a prospective randomized study.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>19076851</pmid><doi>10.1111/j.1751-7133.2008.00020.x</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1527-5299
ispartof Congestive heart failure (Greenwich, Conn.), 2008-11, Vol.14 (6), p.298-301
issn 1527-5299
1751-7133
language eng
recordid cdi_proquest_miscellaneous_69891816
source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Access via Wiley Online Library
subjects Aged
Blood Urea Nitrogen
Creatinine - blood
Female
Heart Failure - blood
Heart Failure - drug therapy
Heart Failure - physiopathology
Heart Failure - therapy
Humans
Length of Stay
Male
Natriuretic Agents - therapeutic use
Natriuretic Peptide, Brain - therapeutic use
Retrospective Studies
Stroke Volume
Ultrafiltration
title Comparison of Ultrafiltration, Nesiritide, and Usual Care in Acute Decompensated Heart Failure
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T04%3A29%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparison%20of%20Ultrafiltration,%20Nesiritide,%20and%20Usual%20Care%20in%20Acute%20Decompensated%20Heart%20Failure&rft.jtitle=Congestive%20heart%20failure%20(Greenwich,%20Conn.)&rft.au=Bartone,%20Cheryl&rft.date=2008-11&rft.volume=14&rft.issue=6&rft.spage=298&rft.epage=301&rft.pages=298-301&rft.issn=1527-5299&rft.eissn=1751-7133&rft_id=info:doi/10.1111/j.1751-7133.2008.00020.x&rft_dat=%3Cproquest_cross%3E69891816%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=69891816&rft_id=info:pmid/19076851&rfr_iscdi=true