Quality of life in nasal polyposis
Background: Nasal polyposis (NP) is a frequent inflammatory chronic disease of the upper respiratory tract, which may impair quality of life (QOL). The NP impact, which is frequently associated with lower respiratory disorders, has never before been studied. Objective: We initiated this prospective...
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| Veröffentlicht in: | Journal of allergy and clinical immunology 1999-07, Vol.104 (1), p.79-84 |
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| container_title | Journal of allergy and clinical immunology |
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| creator | Radenne, Fabienne Lamblin, Catherine Vandezande, Lise-Marie Tillie-Leblond, Isabelle Darras, Jean Tonnel, André-Bernard Wallaert, Benoit |
| description | Background: Nasal polyposis (NP) is a frequent inflammatory chronic disease of the upper respiratory tract, which may impair quality of life (QOL). The NP impact, which is frequently associated with lower respiratory disorders, has never before been studied.
Objective: We initiated this prospective study to establish internal validity and reliability of the generic SF-36 questionnaire in NP and to determine to what level daily functioning becomes impaired as a result of NP.
Methods: Forty-nine consecutive patients with NP were included. They were assessed for the severity of nasal symptoms and underwent pulmonary function tests. The QOL profiles in patients with NP were compared with those of patients with perennial rhinitis (n = 111) and healthy subjects (n = 116).
Results: Cronbach’s coefficient α demonstrated the high reliability and validity of the SF-36 questionnaire for patients with NP (α = .89). NP impaired QOL more than perennial allergic rhinitis (
P < .05). The impairment of QOL was greater when NP was associated with asthma (
P < .05). SF-36 scores appeared highly correlated to pulmonary function (FEV
1 , maximal midexpiratory flow, forced vital capacity), suggesting relationships between QOL in NP and associated bronchial obstruction. Severity of nasal symptoms were not related to QOL scales. In addition, sequential evaluations of QOL, nasal symptoms, and pulmonary function were performed 10 months after the first evaluation in 28 patients with NP. These evaluations demonstrated that NP treatment either with nasal steroids or endonasal ethmoidectomy significantly improved both nasal symptoms and QOL without significant change of pulmonary function.
Conclusion: Our study clearly demonstrated that the SF-36 questionnaire presented a high internal validity and reliability in patients with NP. NP impaired QOL to a greater degree than perennial allergic rhinitis. QOL improvement after NP treatment is related to nasal symptoms improvement. (J Allergy Clin Immunol 1999;103:79-84.) |
| doi_str_mv | 10.1016/S0091-6749(99)70117-X |
| format | Article |
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Objective: We initiated this prospective study to establish internal validity and reliability of the generic SF-36 questionnaire in NP and to determine to what level daily functioning becomes impaired as a result of NP.
Methods: Forty-nine consecutive patients with NP were included. They were assessed for the severity of nasal symptoms and underwent pulmonary function tests. The QOL profiles in patients with NP were compared with those of patients with perennial rhinitis (n = 111) and healthy subjects (n = 116).
Results: Cronbach’s coefficient α demonstrated the high reliability and validity of the SF-36 questionnaire for patients with NP (α = .89). NP impaired QOL more than perennial allergic rhinitis (
P < .05). The impairment of QOL was greater when NP was associated with asthma (
P < .05). SF-36 scores appeared highly correlated to pulmonary function (FEV
1 , maximal midexpiratory flow, forced vital capacity), suggesting relationships between QOL in NP and associated bronchial obstruction. Severity of nasal symptoms were not related to QOL scales. In addition, sequential evaluations of QOL, nasal symptoms, and pulmonary function were performed 10 months after the first evaluation in 28 patients with NP. These evaluations demonstrated that NP treatment either with nasal steroids or endonasal ethmoidectomy significantly improved both nasal symptoms and QOL without significant change of pulmonary function.
Conclusion: Our study clearly demonstrated that the SF-36 questionnaire presented a high internal validity and reliability in patients with NP. NP impaired QOL to a greater degree than perennial allergic rhinitis. QOL improvement after NP treatment is related to nasal symptoms improvement. (J Allergy Clin Immunol 1999;103:79-84.)</description><identifier>ISSN: 0091-6749</identifier><identifier>EISSN: 1097-6825</identifier><identifier>DOI: 10.1016/S0091-6749(99)70117-X</identifier><identifier>PMID: 10400843</identifier><identifier>CODEN: JACIBY</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Adult ; Aged ; asthma ; Biological and medical sciences ; endonasal ethmoidectomy ; Female ; Humans ; Male ; Medical sciences ; Middle Aged ; Nasal polyposis ; Nasal Polyps - psychology ; Non tumoral diseases ; Otorhinolaryngology. Stomatology ; perennial allergic rhinitis ; Psychometrics - methods ; quality of life ; Quality of Life - psychology ; Reproducibility of Results ; SF-36 questionnaire ; Statistics as Topic ; Surveys and Questionnaires ; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</subject><ispartof>Journal of allergy and clinical immunology, 1999-07, Vol.104 (1), p.79-84</ispartof><rights>1999 Mosby, Inc.</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c437t-d1c11dcb03533faf5238881c232491b9849e87432fadf835704a55007b39bee63</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S009167499970117X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1889256$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10400843$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Radenne, Fabienne</creatorcontrib><creatorcontrib>Lamblin, Catherine</creatorcontrib><creatorcontrib>Vandezande, Lise-Marie</creatorcontrib><creatorcontrib>Tillie-Leblond, Isabelle</creatorcontrib><creatorcontrib>Darras, Jean</creatorcontrib><creatorcontrib>Tonnel, André-Bernard</creatorcontrib><creatorcontrib>Wallaert, Benoit</creatorcontrib><title>Quality of life in nasal polyposis</title><title>Journal of allergy and clinical immunology</title><addtitle>J Allergy Clin Immunol</addtitle><description>Background: Nasal polyposis (NP) is a frequent inflammatory chronic disease of the upper respiratory tract, which may impair quality of life (QOL). The NP impact, which is frequently associated with lower respiratory disorders, has never before been studied.
Objective: We initiated this prospective study to establish internal validity and reliability of the generic SF-36 questionnaire in NP and to determine to what level daily functioning becomes impaired as a result of NP.
Methods: Forty-nine consecutive patients with NP were included. They were assessed for the severity of nasal symptoms and underwent pulmonary function tests. The QOL profiles in patients with NP were compared with those of patients with perennial rhinitis (n = 111) and healthy subjects (n = 116).
Results: Cronbach’s coefficient α demonstrated the high reliability and validity of the SF-36 questionnaire for patients with NP (α = .89). NP impaired QOL more than perennial allergic rhinitis (
P < .05). The impairment of QOL was greater when NP was associated with asthma (
P < .05). SF-36 scores appeared highly correlated to pulmonary function (FEV
1 , maximal midexpiratory flow, forced vital capacity), suggesting relationships between QOL in NP and associated bronchial obstruction. Severity of nasal symptoms were not related to QOL scales. In addition, sequential evaluations of QOL, nasal symptoms, and pulmonary function were performed 10 months after the first evaluation in 28 patients with NP. These evaluations demonstrated that NP treatment either with nasal steroids or endonasal ethmoidectomy significantly improved both nasal symptoms and QOL without significant change of pulmonary function.
Conclusion: Our study clearly demonstrated that the SF-36 questionnaire presented a high internal validity and reliability in patients with NP. NP impaired QOL to a greater degree than perennial allergic rhinitis. QOL improvement after NP treatment is related to nasal symptoms improvement. (J Allergy Clin Immunol 1999;103:79-84.)</description><subject>Adult</subject><subject>Aged</subject><subject>asthma</subject><subject>Biological and medical sciences</subject><subject>endonasal ethmoidectomy</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nasal polyposis</subject><subject>Nasal Polyps - psychology</subject><subject>Non tumoral diseases</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>perennial allergic rhinitis</subject><subject>Psychometrics - methods</subject><subject>quality of life</subject><subject>Quality of Life - psychology</subject><subject>Reproducibility of Results</subject><subject>SF-36 questionnaire</subject><subject>Statistics as Topic</subject><subject>Surveys and Questionnaires</subject><subject>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</subject><issn>0091-6749</issn><issn>1097-6825</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF1LwzAUhoMobk5_glJERC-qSZM0yZXI8AsGIirsLqRpApGsrUkr7N_brkO98-pw4HnPxwPAMYJXCKL8-hVCgdKcEXEhxCWDCLF0uQOmCAqW5jyju2D6g0zAQYwfsO8xF_tggiCBkBM8BacvnfKuXSe1TbyzJnFVUqmofNLUft3U0cVDsGeVj-ZoW2fg_f7ubf6YLp4fnua3i1QTzNq0RBqhUhcQU4ytsjTDnHOkM5wRgQrBiTCcEZxZVVqOKYNEUQohK7AojMnxDJyPc5tQf3YmtnLlojbeq8rUXZS54FxkGe5BOoI61DEGY2UT3EqFtURQDnLkRo4cPpdCyI0cuexzJ9sFXbEy5Z_UaKMHzraAilp5G1SlXfzlhv10OPRmxExv48uZIKN2ptKmdMHoVpa1--eSbwoRfn0</recordid><startdate>19990701</startdate><enddate>19990701</enddate><creator>Radenne, Fabienne</creator><creator>Lamblin, Catherine</creator><creator>Vandezande, Lise-Marie</creator><creator>Tillie-Leblond, Isabelle</creator><creator>Darras, Jean</creator><creator>Tonnel, André-Bernard</creator><creator>Wallaert, Benoit</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19990701</creationdate><title>Quality of life in nasal polyposis</title><author>Radenne, Fabienne ; Lamblin, Catherine ; Vandezande, Lise-Marie ; Tillie-Leblond, Isabelle ; Darras, Jean ; Tonnel, André-Bernard ; Wallaert, Benoit</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c437t-d1c11dcb03533faf5238881c232491b9849e87432fadf835704a55007b39bee63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adult</topic><topic>Aged</topic><topic>asthma</topic><topic>Biological and medical sciences</topic><topic>endonasal ethmoidectomy</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nasal polyposis</topic><topic>Nasal Polyps - psychology</topic><topic>Non tumoral diseases</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>perennial allergic rhinitis</topic><topic>Psychometrics - methods</topic><topic>quality of life</topic><topic>Quality of Life - psychology</topic><topic>Reproducibility of Results</topic><topic>SF-36 questionnaire</topic><topic>Statistics as Topic</topic><topic>Surveys and Questionnaires</topic><topic>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Radenne, Fabienne</creatorcontrib><creatorcontrib>Lamblin, Catherine</creatorcontrib><creatorcontrib>Vandezande, Lise-Marie</creatorcontrib><creatorcontrib>Tillie-Leblond, Isabelle</creatorcontrib><creatorcontrib>Darras, Jean</creatorcontrib><creatorcontrib>Tonnel, André-Bernard</creatorcontrib><creatorcontrib>Wallaert, Benoit</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of allergy and clinical immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Radenne, Fabienne</au><au>Lamblin, Catherine</au><au>Vandezande, Lise-Marie</au><au>Tillie-Leblond, Isabelle</au><au>Darras, Jean</au><au>Tonnel, André-Bernard</au><au>Wallaert, Benoit</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quality of life in nasal polyposis</atitle><jtitle>Journal of allergy and clinical immunology</jtitle><addtitle>J Allergy Clin Immunol</addtitle><date>1999-07-01</date><risdate>1999</risdate><volume>104</volume><issue>1</issue><spage>79</spage><epage>84</epage><pages>79-84</pages><issn>0091-6749</issn><eissn>1097-6825</eissn><coden>JACIBY</coden><abstract>Background: Nasal polyposis (NP) is a frequent inflammatory chronic disease of the upper respiratory tract, which may impair quality of life (QOL). The NP impact, which is frequently associated with lower respiratory disorders, has never before been studied.
Objective: We initiated this prospective study to establish internal validity and reliability of the generic SF-36 questionnaire in NP and to determine to what level daily functioning becomes impaired as a result of NP.
Methods: Forty-nine consecutive patients with NP were included. They were assessed for the severity of nasal symptoms and underwent pulmonary function tests. The QOL profiles in patients with NP were compared with those of patients with perennial rhinitis (n = 111) and healthy subjects (n = 116).
Results: Cronbach’s coefficient α demonstrated the high reliability and validity of the SF-36 questionnaire for patients with NP (α = .89). NP impaired QOL more than perennial allergic rhinitis (
P < .05). The impairment of QOL was greater when NP was associated with asthma (
P < .05). SF-36 scores appeared highly correlated to pulmonary function (FEV
1 , maximal midexpiratory flow, forced vital capacity), suggesting relationships between QOL in NP and associated bronchial obstruction. Severity of nasal symptoms were not related to QOL scales. In addition, sequential evaluations of QOL, nasal symptoms, and pulmonary function were performed 10 months after the first evaluation in 28 patients with NP. These evaluations demonstrated that NP treatment either with nasal steroids or endonasal ethmoidectomy significantly improved both nasal symptoms and QOL without significant change of pulmonary function.
Conclusion: Our study clearly demonstrated that the SF-36 questionnaire presented a high internal validity and reliability in patients with NP. NP impaired QOL to a greater degree than perennial allergic rhinitis. QOL improvement after NP treatment is related to nasal symptoms improvement. (J Allergy Clin Immunol 1999;103:79-84.)</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>10400843</pmid><doi>10.1016/S0091-6749(99)70117-X</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of allergy and clinical immunology, 1999-07, Vol.104 (1), p.79-84 |
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| source | Electronic Journals Library; MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Aged asthma Biological and medical sciences endonasal ethmoidectomy Female Humans Male Medical sciences Middle Aged Nasal polyposis Nasal Polyps - psychology Non tumoral diseases Otorhinolaryngology. Stomatology perennial allergic rhinitis Psychometrics - methods quality of life Quality of Life - psychology Reproducibility of Results SF-36 questionnaire Statistics as Topic Surveys and Questionnaires Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology |
| title | Quality of life in nasal polyposis |
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