A Liquid Chromatography-Mass Spectrometry Method for the Simultaneous Measurement of 15 Urinary Estrogens and Estrogen Metabolites: Assay Reproducibility and Interindividual Variability

Background: Accurate, reproducible, and sensitive measurements of endogenous estrogen exposure and individual patterns of estrogen metabolism are needed for etiologic studies of breast cancer. We have developed a high-performance liquid chromatography-tandem mass spectrometry method to quantitate si...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2008-12, Vol.17 (12), p.3411-3418
Hauptverfasser:	Falk, Roni T, Xu, Xia, Keefer, Larry, Veenstra, Timothy D, Ziegler, Regina G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analysis of Variance Chromatography, Liquid - methods estradiol estrogen metabolites Estrogens - urine estrone Female hormonal carcinogenesis Humans interindividual variability Male mass spectrometry Mass Spectrometry - methods Middle Aged reproducibility Reproducibility of Results Sensitivity and Specificity urine
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