Lack of difference in iron status assessed by soluble transferrin receptor between children with cerebral malaria and those with non-cerebral malaria
We conducted this study to determine whether children with cerebral malaria are less likely to have tissue iron deficiency than those with non-cerebral malaria. Iron status was assessed by soluble transferrin receptor (sTfR), serum ferritin, and haemoglobin in 44 Zaïrian children: 15 with cerebral m...
Gespeichert in:
| Veröffentlicht in: | Journal of tropical pediatrics (1980) 1999-06, Vol.45 (3), p.166-167 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 167 |
|---|---|
| container_issue | 3 |
| container_start_page | 166 |
| container_title | Journal of tropical pediatrics (1980) |
| container_volume | 45 |
| creator | KIVIBIDILA, S WARRIER, R. P ODE, D YU, L TSHEFU, K. A |
| description | We conducted this study to determine whether children with cerebral malaria are less likely to have tissue iron deficiency than those with non-cerebral malaria. Iron status was assessed by soluble transferrin receptor (sTfR), serum ferritin, and haemoglobin in 44 Zaïrian children: 15 with cerebral malaria, 14 with non-cerebral malaria, and 15 without malaria (age range 0.5-16 years). Although there was no significant difference in the mean concentrations of sTfR, serum ferritin, or haemoglobin between either group of patients, a higher percentage of children with cerebral malaria (27 per cent) than those with non-cerebral malaria (14 per cent) or controls (7%) had sTfR levels above 7.3 mg/l (suggestive of tissue iron deficiency). A higher percentage of children with cerebral malaria (40 per cent) than with non-cerebral malaria (29 per cent) or controls (20 per cent) also had either serum ferritin < 100 micrograms/l and inflammation or sTfR > 7.3 mg/l or both. The data suggest that children with cerebral malaria are as likely to have tissue iron deficiency as those with non-cerebral malaria. |
| doi_str_mv | 10.1093/tropej/45.3.166 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_69883646</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69883646</sourcerecordid><originalsourceid>FETCH-LOGICAL-p236t-fad985a5bdc5c34457407a41f9230e5bf12d8fd6879bfadd300e3aa4fc0777b63</originalsourceid><addsrcrecordid>eNpd0MFrFDEUBvBQlHZtPXuTHKS32SaTTCZzlKK1sNCLPS8vyQubmk3GJEPpH-L_60hXBOHBd3g_vsNHyAfOtpxN4qaVPOPTjRy2YsuVOiMbLtXQCaXkG7JhXPadEkJfkHe1PjHGei3lObngTDLOJ7Uhv3Zgf9DsqQveY8FkkYZEQ8mJ1gZtqRRqxfUcNS-05riYiLQVSHX1ZbUFLc4tF2qwPSMmag8hurWKPod2oHZtNQUiPUKEEoBCcrQdcsXXf8qp-99ckbceYsX3p7wkj1-_fL_91u0e7u5vP--6uReqdR7cpAcYjLODFVIOo2QjSO6nXjAcjOe9094pPU5mtU4whgJAesvGcTRKXJLr19655J8L1rY_hmoxRkiYl7pXk9ZCyT_w4wku5ohuP5dwhPKy_zvkCj6dAFQL0a_72FD_OS16rqX4DTGShps</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69883646</pqid></control><display><type>article</type><title>Lack of difference in iron status assessed by soluble transferrin receptor between children with cerebral malaria and those with non-cerebral malaria</title><source>MEDLINE</source><source>Oxford University Press Journals All Titles (1996-Current)</source><creator>KIVIBIDILA, S ; WARRIER, R. P ; ODE, D ; YU, L ; TSHEFU, K. A</creator><creatorcontrib>KIVIBIDILA, S ; WARRIER, R. P ; ODE, D ; YU, L ; TSHEFU, K. A</creatorcontrib><description>We conducted this study to determine whether children with cerebral malaria are less likely to have tissue iron deficiency than those with non-cerebral malaria. Iron status was assessed by soluble transferrin receptor (sTfR), serum ferritin, and haemoglobin in 44 Zaïrian children: 15 with cerebral malaria, 14 with non-cerebral malaria, and 15 without malaria (age range 0.5-16 years). Although there was no significant difference in the mean concentrations of sTfR, serum ferritin, or haemoglobin between either group of patients, a higher percentage of children with cerebral malaria (27 per cent) than those with non-cerebral malaria (14 per cent) or controls (7%) had sTfR levels above 7.3 mg/l (suggestive of tissue iron deficiency). A higher percentage of children with cerebral malaria (40 per cent) than with non-cerebral malaria (29 per cent) or controls (20 per cent) also had either serum ferritin < 100 micrograms/l and inflammation or sTfR > 7.3 mg/l or both. The data suggest that children with cerebral malaria are as likely to have tissue iron deficiency as those with non-cerebral malaria.</description><identifier>ISSN: 0142-6338</identifier><identifier>EISSN: 1465-3664</identifier><identifier>DOI: 10.1093/tropej/45.3.166</identifier><identifier>PMID: 10401196</identifier><identifier>CODEN: JTRPAO</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Adolescent ; Anemia, Iron-Deficiency - blood ; Anemia, Iron-Deficiency - etiology ; Biological and medical sciences ; Case-Control Studies ; Child ; Child, Preschool ; Cross-Sectional Studies ; Female ; Ferritins - blood ; Hemoglobins - analysis ; Human protozoal diseases ; Humans ; Infant ; Infectious diseases ; Inflammation ; Malaria ; Malaria, Cerebral - complications ; Malaria, Cerebral - immunology ; Malaria, Falciparum - complications ; Malaria, Falciparum - immunology ; Male ; Medical sciences ; Parasitic diseases ; Protozoal diseases ; Receptors, Transferrin - blood ; Tropical medicine</subject><ispartof>Journal of tropical pediatrics (1980), 1999-06, Vol.45 (3), p.166-167</ispartof><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1832184$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10401196$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KIVIBIDILA, S</creatorcontrib><creatorcontrib>WARRIER, R. P</creatorcontrib><creatorcontrib>ODE, D</creatorcontrib><creatorcontrib>YU, L</creatorcontrib><creatorcontrib>TSHEFU, K. A</creatorcontrib><title>Lack of difference in iron status assessed by soluble transferrin receptor between children with cerebral malaria and those with non-cerebral malaria</title><title>Journal of tropical pediatrics (1980)</title><addtitle>J Trop Pediatr</addtitle><description>We conducted this study to determine whether children with cerebral malaria are less likely to have tissue iron deficiency than those with non-cerebral malaria. Iron status was assessed by soluble transferrin receptor (sTfR), serum ferritin, and haemoglobin in 44 Zaïrian children: 15 with cerebral malaria, 14 with non-cerebral malaria, and 15 without malaria (age range 0.5-16 years). Although there was no significant difference in the mean concentrations of sTfR, serum ferritin, or haemoglobin between either group of patients, a higher percentage of children with cerebral malaria (27 per cent) than those with non-cerebral malaria (14 per cent) or controls (7%) had sTfR levels above 7.3 mg/l (suggestive of tissue iron deficiency). A higher percentage of children with cerebral malaria (40 per cent) than with non-cerebral malaria (29 per cent) or controls (20 per cent) also had either serum ferritin < 100 micrograms/l and inflammation or sTfR > 7.3 mg/l or both. The data suggest that children with cerebral malaria are as likely to have tissue iron deficiency as those with non-cerebral malaria.</description><subject>Adolescent</subject><subject>Anemia, Iron-Deficiency - blood</subject><subject>Anemia, Iron-Deficiency - etiology</subject><subject>Biological and medical sciences</subject><subject>Case-Control Studies</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Ferritins - blood</subject><subject>Hemoglobins - analysis</subject><subject>Human protozoal diseases</subject><subject>Humans</subject><subject>Infant</subject><subject>Infectious diseases</subject><subject>Inflammation</subject><subject>Malaria</subject><subject>Malaria, Cerebral - complications</subject><subject>Malaria, Cerebral - immunology</subject><subject>Malaria, Falciparum - complications</subject><subject>Malaria, Falciparum - immunology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Parasitic diseases</subject><subject>Protozoal diseases</subject><subject>Receptors, Transferrin - blood</subject><subject>Tropical medicine</subject><issn>0142-6338</issn><issn>1465-3664</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpd0MFrFDEUBvBQlHZtPXuTHKS32SaTTCZzlKK1sNCLPS8vyQubmk3GJEPpH-L_60hXBOHBd3g_vsNHyAfOtpxN4qaVPOPTjRy2YsuVOiMbLtXQCaXkG7JhXPadEkJfkHe1PjHGei3lObngTDLOJ7Uhv3Zgf9DsqQveY8FkkYZEQ8mJ1gZtqRRqxfUcNS-05riYiLQVSHX1ZbUFLc4tF2qwPSMmag8hurWKPod2oHZtNQUiPUKEEoBCcrQdcsXXf8qp-99ckbceYsX3p7wkj1-_fL_91u0e7u5vP--6uReqdR7cpAcYjLODFVIOo2QjSO6nXjAcjOe9094pPU5mtU4whgJAesvGcTRKXJLr19655J8L1rY_hmoxRkiYl7pXk9ZCyT_w4wku5ohuP5dwhPKy_zvkCj6dAFQL0a_72FD_OS16rqX4DTGShps</recordid><startdate>19990601</startdate><enddate>19990601</enddate><creator>KIVIBIDILA, S</creator><creator>WARRIER, R. P</creator><creator>ODE, D</creator><creator>YU, L</creator><creator>TSHEFU, K. A</creator><general>Oxford University Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19990601</creationdate><title>Lack of difference in iron status assessed by soluble transferrin receptor between children with cerebral malaria and those with non-cerebral malaria</title><author>KIVIBIDILA, S ; WARRIER, R. P ; ODE, D ; YU, L ; TSHEFU, K. A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p236t-fad985a5bdc5c34457407a41f9230e5bf12d8fd6879bfadd300e3aa4fc0777b63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adolescent</topic><topic>Anemia, Iron-Deficiency - blood</topic><topic>Anemia, Iron-Deficiency - etiology</topic><topic>Biological and medical sciences</topic><topic>Case-Control Studies</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Ferritins - blood</topic><topic>Hemoglobins - analysis</topic><topic>Human protozoal diseases</topic><topic>Humans</topic><topic>Infant</topic><topic>Infectious diseases</topic><topic>Inflammation</topic><topic>Malaria</topic><topic>Malaria, Cerebral - complications</topic><topic>Malaria, Cerebral - immunology</topic><topic>Malaria, Falciparum - complications</topic><topic>Malaria, Falciparum - immunology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Parasitic diseases</topic><topic>Protozoal diseases</topic><topic>Receptors, Transferrin - blood</topic><topic>Tropical medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KIVIBIDILA, S</creatorcontrib><creatorcontrib>WARRIER, R. P</creatorcontrib><creatorcontrib>ODE, D</creatorcontrib><creatorcontrib>YU, L</creatorcontrib><creatorcontrib>TSHEFU, K. A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of tropical pediatrics (1980)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KIVIBIDILA, S</au><au>WARRIER, R. P</au><au>ODE, D</au><au>YU, L</au><au>TSHEFU, K. A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lack of difference in iron status assessed by soluble transferrin receptor between children with cerebral malaria and those with non-cerebral malaria</atitle><jtitle>Journal of tropical pediatrics (1980)</jtitle><addtitle>J Trop Pediatr</addtitle><date>1999-06-01</date><risdate>1999</risdate><volume>45</volume><issue>3</issue><spage>166</spage><epage>167</epage><pages>166-167</pages><issn>0142-6338</issn><eissn>1465-3664</eissn><coden>JTRPAO</coden><abstract>We conducted this study to determine whether children with cerebral malaria are less likely to have tissue iron deficiency than those with non-cerebral malaria. Iron status was assessed by soluble transferrin receptor (sTfR), serum ferritin, and haemoglobin in 44 Zaïrian children: 15 with cerebral malaria, 14 with non-cerebral malaria, and 15 without malaria (age range 0.5-16 years). Although there was no significant difference in the mean concentrations of sTfR, serum ferritin, or haemoglobin between either group of patients, a higher percentage of children with cerebral malaria (27 per cent) than those with non-cerebral malaria (14 per cent) or controls (7%) had sTfR levels above 7.3 mg/l (suggestive of tissue iron deficiency). A higher percentage of children with cerebral malaria (40 per cent) than with non-cerebral malaria (29 per cent) or controls (20 per cent) also had either serum ferritin < 100 micrograms/l and inflammation or sTfR > 7.3 mg/l or both. The data suggest that children with cerebral malaria are as likely to have tissue iron deficiency as those with non-cerebral malaria.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>10401196</pmid><doi>10.1093/tropej/45.3.166</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0142-6338 |
| ispartof | Journal of tropical pediatrics (1980), 1999-06, Vol.45 (3), p.166-167 |
| issn | 0142-6338 1465-3664 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69883646 |
| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current) |
| subjects | Adolescent Anemia, Iron-Deficiency - blood Anemia, Iron-Deficiency - etiology Biological and medical sciences Case-Control Studies Child Child, Preschool Cross-Sectional Studies Female Ferritins - blood Hemoglobins - analysis Human protozoal diseases Humans Infant Infectious diseases Inflammation Malaria Malaria, Cerebral - complications Malaria, Cerebral - immunology Malaria, Falciparum - complications Malaria, Falciparum - immunology Male Medical sciences Parasitic diseases Protozoal diseases Receptors, Transferrin - blood Tropical medicine |
| title | Lack of difference in iron status assessed by soluble transferrin receptor between children with cerebral malaria and those with non-cerebral malaria |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T02%3A30%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lack%20of%20difference%20in%20iron%20status%20assessed%20by%20soluble%20transferrin%20receptor%20between%20children%20with%20cerebral%20malaria%20and%20those%20with%20non-cerebral%20malaria&rft.jtitle=Journal%20of%20tropical%20pediatrics%20(1980)&rft.au=KIVIBIDILA,%20S&rft.date=1999-06-01&rft.volume=45&rft.issue=3&rft.spage=166&rft.epage=167&rft.pages=166-167&rft.issn=0142-6338&rft.eissn=1465-3664&rft.coden=JTRPAO&rft_id=info:doi/10.1093/tropej/45.3.166&rft_dat=%3Cproquest_pubme%3E69883646%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=69883646&rft_id=info:pmid/10401196&rfr_iscdi=true |