Timp-1 Is Important for Epithelial Proliferation and Branching Morphogenesis during Mouse Mammary Development

The dynamic process of mammary ductal morphogenesis depends on regulated epithelial proliferation and extracellular matrix (ECM) turnover. Epithelial cell–matrix contact closely dictates epithelial proliferation, differentiation, and survival. Despite the fact that tissue inhibitors of metalloprotei...

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Veröffentlicht in:	Developmental biology 1999-07, Vol.211 (2), p.238-254
Hauptverfasser:	Fata, Jimmie E., Leco, Kevin J., Moorehead, Roger A., Martin, David C., Khokha, Rama
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Epithelial Cells - cytology Epithelial Cells - physiology epithelial proliferation Female Gene Expression Regulation, Developmental - physiology Immunohistochemistry Mammary Glands, Animal - embryology Mammary Glands, Animal - physiology mammary morphogenesis Mice Morphogenesis RNA, Messenger - analysis Timps Tissue Inhibitor of Metalloproteinase-1 - physiology transgenic mice
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