Combining mortality and longitudinal measures in clinical trials

Clinical trials often assess therapeutic benefit on the basis of an event such as death or the diagnosis of disease. Usually, there are several additional longitudinal measures of clinical status which are collected to be used in the treatment comparison. This paper proposes a simple non‐parametric...

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Veröffentlicht in:	Statistics in medicine 1999-06, Vol.18 (11), p.1341-1354
Hauptverfasser:	Finkelstein, Dianne M., Schoenfeld, David A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - mortality AIDS/HIV Anti-HIV Agents - therapeutic use Anti-Infective Agents - therapeutic use Antifungal Agents - therapeutic use Biological and medical sciences Candidiasis - prevention & control Child Child, Preschool Clinical trial. Drug monitoring Clinical Trials as Topic - statistics & numerical data Clotrimazole - therapeutic use Computerized, statistical medical data processing and models in biomedicine Dapsone - therapeutic use Didanosine - therapeutic use Drug Therapy, Combination Fluconazole - therapeutic use General pharmacology Head - growth & development Humans Longitudinal Studies Medical sciences Medical statistics Pentamidine - therapeutic use Pharmacology. Drug treatments Pneumonia, Pneumocystis - prevention & control Statistics, Nonparametric Treatment Outcome Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use Zidovudine - therapeutic use
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