Guided tours: from precursor snoRNA to functional snoRNP

Small nucleolar RNAs (snoRNAs) use base pairing to guide modification of conserved nucleotides in functionally important regions of ribosomal RNA. The box C/D snoRNAs direct 2′-O-methylation and the box H/ACA snoRNAs direct pseudouridylation. Each snoRNA interacts with proteins, many of them newly i...

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Veröffentlicht in:	Current opinion in cell biology 1999-06, Vol.11 (3), p.378-384
Hauptverfasser:	Weinstein, Lara B, Steitz, Joan A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Nucleolus - metabolism Humans Ribonucleoproteins, Small Nuclear - metabolism RNA Precursors - genetics RNA Precursors - metabolism RNA, Small Nuclear - metabolism Transcription, Genetic
Online-Zugang:	Volltext
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