Changes in Regulatory MicroRNA Expression in Myocardium of Heart Failure Patients on Left Ventricular Assist Device Support

Background Left ventricular assist device support in heart failure patients leads to changes in mRNA and protein expression in the myocardium. Methods MicroRNA's are important regulators of various cellular processes, so changes in their expression were tested by Q-PCR methods. Results LVAD sup...

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Veröffentlicht in:	The Journal of heart and lung transplantation 2008-12, Vol.27 (12), p.1282-1285
Hauptverfasser:	Schipper, Marguérite E.I., MD, van Kuik, Joyce, BSc, de Jonge, Nicholas, MD, PhD, Dullens, Hub F.J., PhD, de Weger, Roel A., PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Autopsy Biological and medical sciences Cardiology. Vascular system Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care Female Heart Heart - physiopathology Heart Failure - genetics Heart Failure - surgery Heart failure, cardiogenic pulmonary edema, cardiac enlargement Heart Transplantation Heart-Assist Devices Humans Intensive care medicine Male Medical sciences MicroRNAs - genetics MicroRNAs - isolation & purification Middle Aged Myocardium - pathology Reference Values Reverse Transcriptase Polymerase Chain Reaction RNA - genetics RNA - isolation & purification Surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Tissue Donors Ventricular Dysfunction, Left - genetics Ventricular Dysfunction, Left - physiopathology Ventricular Dysfunction, Left - surgery
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