The effects of quinine and 4-aminopyridine on conditioned place preference and changes in motor activity induced by morphine in rats

1. 1. The effects of two unselective potassium (K +-) channel blockers, quinine (12.5, 25 and 50 mg/kg) and 4-aminopyridine (1 and 2 mg/kg), on conditioned place preference and biphasic changes in motor activity induced by morphine (10 mg/kg) were tested in Wistar rats. Quinine is known to block vol...

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Veröffentlicht in:	Progress in neuro-psychopharmacology & biological psychiatry 1999-05, Vol.23 (4), p.713-730
Hauptverfasser:	Meririnne, Esa, Kankaanpää, Aino, Vanakoski, Jyrki, Lillsunde, Pirjo, Seppälä, Timo
Format:	Artikel
Sprache:	eng
Schlagworte:	4-aminopyridine 4-Aminopyridine - pharmacology Analgesics Analysis of Variance Animals Behavioral psychophysiology Biological and medical sciences conditioned place preference Conditioning, Operant - drug effects Fundamental and applied biological sciences. Psychology Male Medical sciences morphine Morphine - pharmacology motor activity Motor Activity - drug effects Neuropharmacology Neurotransmission and behavior Pharmacology. Drug treatments Potassium Channel Blockers potassium channels Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology quinine Quinine - pharmacology Rats Rats, Wistar reward
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