Genetic variants in the HLA-G region are associated with Kawasaki disease

Abstract Kawasaki disease is an acute, self-limited vasculitis of infants and children, manifest as fever and signs of mucocutaneous inflammation. Treatment with high-dose immunoglobulin reduces systemic inflammation and prevents coronary artery lesions in Kawasaki disease. In this study, we investi...

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Veröffentlicht in:	Human immunology 2008-12, Vol.69 (12), p.867-871
Hauptverfasser:	Kim, Jae-Jung, Hong, Soo-Jong, Hong, Young Mi, Kim, Sun, Kang, Mi-Jin, Kim, Kwi-Joo, Seo, Eul-Joo, Yoo, Han-Wook, Cheong, Hyun-Sub, Shin, Hyoung-Doo, Park, In-Sook, Lee, Jong-Keuk
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Chromosome Mapping Coronary Aneurysm - etiology Coronary Aneurysm - genetics DNA Mutational Analysis Genetic Predisposition to Disease Genetic Testing Germany Histocompatibility Antigens Class I - genetics Histocompatibility Antigens Class I - immunology HLA Antigens - genetics HLA Antigens - immunology HLA-G HLA-G Antigens Humans Kawasaki disease Linkage Disequilibrium Major histocompatibility complex Mucocutaneous Lymph Node Syndrome - complications Mucocutaneous Lymph Node Syndrome - genetics Mucocutaneous Lymph Node Syndrome - immunology Mucocutaneous Lymph Node Syndrome - physiopathology Polymorphism, Single Nucleotide Single nucleotide polymorphism
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