Functional Residual Capacity and Pulmonary Mechanics in Premature Infants Receiving a 12-Day Dexamethasone Course
ABSTRACT The objective of this paper is to determine the effects of a 12-day dexamethasone course of the pulmonary function of preterm infants. The design consisted of a consecutive sample of eligible patients, before-after trial. The Regional referral center neonatal ICU was the setting. The patien...
Gespeichert in:
| Veröffentlicht in: | American journal of perinatology 1999, Vol.16 (3), p.151-156 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 156 |
|---|---|
| container_issue | 3 |
| container_start_page | 151 |
| container_title | American journal of perinatology |
| container_volume | 16 |
| creator | Lee, Modestus Diah, Paulett Krauss, Alfred N. Auld, Peter A.M. |
| description | ABSTRACT
The objective of this paper is to determine the effects of a 12-day dexamethasone course of the pulmonary function of preterm infants. The design consisted of a consecutive sample of eligible patients, before-after trial. The Regional referral center neonatal ICU was the setting. The patients were 13 preterm infants, 545-1315 g, requiring mechanical ventilation. The following was used: Intravenous dexamethasone for a 12-day tapering course beginning at 0.5 mglkg every 12 hr. Main outcome measures were as follows: Measurements of functional residual capacity (FRC), compliance, resistance, arterial blood gases and alveolar-arterial differences, level of ventilatory assistance, weight, length. All measures of pulmonary function demonstrated significant improvement by Day 12 of treatment. Most improvement occurred in the first 6 days of treatment, in association with increased lung volume. |
| doi_str_mv | 10.1055/s-2007-993849 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69854532</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69854532</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2709-82e8513f0fc8d815f9cf54961665947d1946dbaa34b282e9df1613f1170118bb3</originalsourceid><addsrcrecordid>eNp10cFu1DAQBmALUdFt4cgV-YA4NcWTxIl9RFsKlYqoEJytiTNmXSXO1k5Q9-1xlZXg0pMtzecZzW_G3oK4BCHlx1SUQrSF1pWq9Qu2AaFVoVolX7KNaCtZQFPBKTtL6V4IKJVQr9gpiLpSoNsNe7hegp39FHDgPyj5fsmXLe7R-vnAMfT8bhnGXI4H_o3sDoO3ifvA7yKNOC-R-E1wGOaUn1vyf3z4zZFDWVzhgV_RI4407zBNgfh2WmKi1-zE4ZDozfE8Z7-uP__cfi1uv3-52X66LWzZCl2okpSEyglnVa9AOm2drHUDTSN13fag66bvEKu6K7PVvYMmc4BWAKiuq87Zh7XvPk4PC6XZjD5ZGgYMNC3JNFrJWlZlhsUKbZxSiuTMPvoxL2xAmKeMTTJPGZs14-zfHRsv3Uj9f3oNNYP3R4DJ4uAiBuvTP6caJVuR2cXK5p2nkcx9jid_Q3pm7F8beZEu</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69854532</pqid></control><display><type>article</type><title>Functional Residual Capacity and Pulmonary Mechanics in Premature Infants Receiving a 12-Day Dexamethasone Course</title><source>MEDLINE</source><source>Thieme Connect Journals</source><creator>Lee, Modestus ; Diah, Paulett ; Krauss, Alfred N. ; Auld, Peter A.M.</creator><creatorcontrib>Lee, Modestus ; Diah, Paulett ; Krauss, Alfred N. ; Auld, Peter A.M.</creatorcontrib><description>ABSTRACT
The objective of this paper is to determine the effects of a 12-day dexamethasone course of the pulmonary function of preterm infants. The design consisted of a consecutive sample of eligible patients, before-after trial. The Regional referral center neonatal ICU was the setting. The patients were 13 preterm infants, 545-1315 g, requiring mechanical ventilation. The following was used: Intravenous dexamethasone for a 12-day tapering course beginning at 0.5 mglkg every 12 hr. Main outcome measures were as follows: Measurements of functional residual capacity (FRC), compliance, resistance, arterial blood gases and alveolar-arterial differences, level of ventilatory assistance, weight, length. All measures of pulmonary function demonstrated significant improvement by Day 12 of treatment. Most improvement occurred in the first 6 days of treatment, in association with increased lung volume.</description><identifier>ISSN: 0735-1631</identifier><identifier>EISSN: 1098-8785</identifier><identifier>DOI: 10.1055/s-2007-993849</identifier><identifier>PMID: 10438197</identifier><identifier>CODEN: AJPEEK</identifier><language>eng</language><publisher>New York, NY: Thieme</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Anti-Inflammatory Agents - therapeutic use ; Biological and medical sciences ; Dexamethasone - therapeutic use ; Emergency and intensive care: neonates and children. Prematurity. Sudden death ; Female ; Functional Residual Capacity ; Humans ; Infant, Newborn ; Infant, Premature ; Intensive care medicine ; Male ; Medical sciences ; ORIGINAL ARTICLE ; Respiratory Distress Syndrome, Newborn - drug therapy ; Respiratory Distress Syndrome, Newborn - physiopathology ; Respiratory Mechanics</subject><ispartof>American journal of perinatology, 1999, Vol.16 (3), p.151-156</ispartof><rights>1999 by Thieme Medical Publishers, Inc.</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2709-82e8513f0fc8d815f9cf54961665947d1946dbaa34b282e9df1613f1170118bb3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2007-993849.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><linktohtml>$$Uhttps://www.thieme-connect.de/products/ejournals/html/10.1055/s-2007-993849$$EHTML$$P50$$Gthieme$$H</linktohtml><link.rule.ids>309,310,314,776,780,785,786,3004,3005,4010,4036,4037,23909,23910,25118,27900,27901,27902,54534,54535</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1868570$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10438197$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Modestus</creatorcontrib><creatorcontrib>Diah, Paulett</creatorcontrib><creatorcontrib>Krauss, Alfred N.</creatorcontrib><creatorcontrib>Auld, Peter A.M.</creatorcontrib><title>Functional Residual Capacity and Pulmonary Mechanics in Premature Infants Receiving a 12-Day Dexamethasone Course</title><title>American journal of perinatology</title><addtitle>Amer J Perinatol</addtitle><description>ABSTRACT
The objective of this paper is to determine the effects of a 12-day dexamethasone course of the pulmonary function of preterm infants. The design consisted of a consecutive sample of eligible patients, before-after trial. The Regional referral center neonatal ICU was the setting. The patients were 13 preterm infants, 545-1315 g, requiring mechanical ventilation. The following was used: Intravenous dexamethasone for a 12-day tapering course beginning at 0.5 mglkg every 12 hr. Main outcome measures were as follows: Measurements of functional residual capacity (FRC), compliance, resistance, arterial blood gases and alveolar-arterial differences, level of ventilatory assistance, weight, length. All measures of pulmonary function demonstrated significant improvement by Day 12 of treatment. Most improvement occurred in the first 6 days of treatment, in association with increased lung volume.</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Anti-Inflammatory Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Dexamethasone - therapeutic use</subject><subject>Emergency and intensive care: neonates and children. Prematurity. Sudden death</subject><subject>Female</subject><subject>Functional Residual Capacity</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infant, Premature</subject><subject>Intensive care medicine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>ORIGINAL ARTICLE</subject><subject>Respiratory Distress Syndrome, Newborn - drug therapy</subject><subject>Respiratory Distress Syndrome, Newborn - physiopathology</subject><subject>Respiratory Mechanics</subject><issn>0735-1631</issn><issn>1098-8785</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10cFu1DAQBmALUdFt4cgV-YA4NcWTxIl9RFsKlYqoEJytiTNmXSXO1k5Q9-1xlZXg0pMtzecZzW_G3oK4BCHlx1SUQrSF1pWq9Qu2AaFVoVolX7KNaCtZQFPBKTtL6V4IKJVQr9gpiLpSoNsNe7hegp39FHDgPyj5fsmXLe7R-vnAMfT8bhnGXI4H_o3sDoO3ifvA7yKNOC-R-E1wGOaUn1vyf3z4zZFDWVzhgV_RI4407zBNgfh2WmKi1-zE4ZDozfE8Z7-uP__cfi1uv3-52X66LWzZCl2okpSEyglnVa9AOm2drHUDTSN13fag66bvEKu6K7PVvYMmc4BWAKiuq87Zh7XvPk4PC6XZjD5ZGgYMNC3JNFrJWlZlhsUKbZxSiuTMPvoxL2xAmKeMTTJPGZs14-zfHRsv3Uj9f3oNNYP3R4DJ4uAiBuvTP6caJVuR2cXK5p2nkcx9jid_Q3pm7F8beZEu</recordid><startdate>1999</startdate><enddate>1999</enddate><creator>Lee, Modestus</creator><creator>Diah, Paulett</creator><creator>Krauss, Alfred N.</creator><creator>Auld, Peter A.M.</creator><general>Thieme</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1999</creationdate><title>Functional Residual Capacity and Pulmonary Mechanics in Premature Infants Receiving a 12-Day Dexamethasone Course</title><author>Lee, Modestus ; Diah, Paulett ; Krauss, Alfred N. ; Auld, Peter A.M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2709-82e8513f0fc8d815f9cf54961665947d1946dbaa34b282e9df1613f1170118bb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Anti-Inflammatory Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Dexamethasone - therapeutic use</topic><topic>Emergency and intensive care: neonates and children. Prematurity. Sudden death</topic><topic>Female</topic><topic>Functional Residual Capacity</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Infant, Premature</topic><topic>Intensive care medicine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>ORIGINAL ARTICLE</topic><topic>Respiratory Distress Syndrome, Newborn - drug therapy</topic><topic>Respiratory Distress Syndrome, Newborn - physiopathology</topic><topic>Respiratory Mechanics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Modestus</creatorcontrib><creatorcontrib>Diah, Paulett</creatorcontrib><creatorcontrib>Krauss, Alfred N.</creatorcontrib><creatorcontrib>Auld, Peter A.M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of perinatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Modestus</au><au>Diah, Paulett</au><au>Krauss, Alfred N.</au><au>Auld, Peter A.M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Functional Residual Capacity and Pulmonary Mechanics in Premature Infants Receiving a 12-Day Dexamethasone Course</atitle><jtitle>American journal of perinatology</jtitle><addtitle>Amer J Perinatol</addtitle><date>1999</date><risdate>1999</risdate><volume>16</volume><issue>3</issue><spage>151</spage><epage>156</epage><pages>151-156</pages><issn>0735-1631</issn><eissn>1098-8785</eissn><coden>AJPEEK</coden><abstract>ABSTRACT
The objective of this paper is to determine the effects of a 12-day dexamethasone course of the pulmonary function of preterm infants. The design consisted of a consecutive sample of eligible patients, before-after trial. The Regional referral center neonatal ICU was the setting. The patients were 13 preterm infants, 545-1315 g, requiring mechanical ventilation. The following was used: Intravenous dexamethasone for a 12-day tapering course beginning at 0.5 mglkg every 12 hr. Main outcome measures were as follows: Measurements of functional residual capacity (FRC), compliance, resistance, arterial blood gases and alveolar-arterial differences, level of ventilatory assistance, weight, length. All measures of pulmonary function demonstrated significant improvement by Day 12 of treatment. Most improvement occurred in the first 6 days of treatment, in association with increased lung volume.</abstract><cop>New York, NY</cop><pub>Thieme</pub><pmid>10438197</pmid><doi>10.1055/s-2007-993849</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0735-1631 |
| ispartof | American journal of perinatology, 1999, Vol.16 (3), p.151-156 |
| issn | 0735-1631 1098-8785 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69854532 |
| source | MEDLINE; Thieme Connect Journals |
| subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anti-Inflammatory Agents - therapeutic use Biological and medical sciences Dexamethasone - therapeutic use Emergency and intensive care: neonates and children. Prematurity. Sudden death Female Functional Residual Capacity Humans Infant, Newborn Infant, Premature Intensive care medicine Male Medical sciences ORIGINAL ARTICLE Respiratory Distress Syndrome, Newborn - drug therapy Respiratory Distress Syndrome, Newborn - physiopathology Respiratory Mechanics |
| title | Functional Residual Capacity and Pulmonary Mechanics in Premature Infants Receiving a 12-Day Dexamethasone Course |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T23%3A12%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Functional%20Residual%20Capacity%20and%20Pulmonary%20Mechanics%20in%20Premature%20Infants%20Receiving%20a%2012-Day%20Dexamethasone%20Course&rft.jtitle=American%20journal%20of%20perinatology&rft.au=Lee,%20Modestus&rft.date=1999&rft.volume=16&rft.issue=3&rft.spage=151&rft.epage=156&rft.pages=151-156&rft.issn=0735-1631&rft.eissn=1098-8785&rft.coden=AJPEEK&rft_id=info:doi/10.1055/s-2007-993849&rft_dat=%3Cproquest_cross%3E69854532%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=69854532&rft_id=info:pmid/10438197&rfr_iscdi=true |