Evidence for Phosphatidylinositol 4‐Kinase and Actin Involvement in the Regulation of 125I‐β‐Nerve Growth Factor Retrograde Axonal Transport

: The signaling events regulating the retrograde axonal transport of neurotrophins are poorly understood, but a role for phosphatidylinositol kinases has been proposed. In this study, we used phenylarsine oxide (PAO) to examine the participation of phosphatidylinositol 4‐kinases in nerve growth fact...

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Veröffentlicht in:	Journal of neurochemistry 1999-07, Vol.73 (1), p.87-95
Hauptverfasser:	Reynolds, Anna J., Heydon, Katharina, Bartlett, Selena E., Hendry, Ian A.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 4-Kinase - antagonists & inhibitors 1-Phosphatidylinositol 4-Kinase - metabolism Actin cytoskeleton Actins - chemistry Actins - metabolism Animals Arsenicals - pharmacology Axonal Transport - drug effects Axonal Transport - physiology Biological and medical sciences Cell physiology Cell Survival - drug effects Cytoskeleton - chemistry Cytoskeleton - drug effects Cytoskeleton - physiology Enzyme Inhibitors - pharmacology Fundamental and applied biological sciences. Psychology Iodine Radioisotopes Isoenzymes - antagonists & inhibitors Isoenzymes - metabolism Male Membrane and intracellular transports Mice Mice, Inbred CBA Molecular and cellular biology Nerve growth factor Nerve Growth Factors - metabolism Neuronal survival Neurons - metabolism Neurons, Afferent - metabolism Phenylarsine oxide Phosphatidylinositol 4‐kinase Retrograde axonal transport Signal Transduction Superior Cervical Ganglion - metabolism
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