Acyl-CoA synthetase catalyzes the synthesis of diadenosine hexaphosphate (Ap 6A)

The synthesis of diadenosine hexaphosphate (Ap 6A), a potent vasoconstrictor, is catalyzed by acyl-CoA synthetase from Pseudomonas fragi. In a first step AMP is transferred from ATP to tetrapolyphosphate (P 4) originating adenosine pentaphosphate (p 5A) which, subsequently, is the acceptor of anothe...

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Veröffentlicht in:	Biochimie 1999-03, Vol.81 (3), p.229-233
Hauptverfasser:	Fontes, Rui, Günther Sillero, María A, Sillero, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	acyl-CoA synthetase Catalysis Coenzyme A Ligases - metabolism diadenosine hexaphosphate diadenosine pentaphosphate Dinucleoside Phosphates - biosynthesis dinucleoside polyphosphates Pseudomonas - enzymology Pseudomonas fragi
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