Dynamic correlation of apoptosis and immune activation during treatment of HIV infection

T cells from HIV infected patients undergo spontaneous apoptosis at a faster rate than those from uninfected patients, are abnormally susceptible to activation induced cell death (AICD), and undergo increased apoptosis in response to Fas receptor ligation. These observations have led to the hypothes...

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Veröffentlicht in:	Cell death and differentiation 1999-05, Vol.6 (5), p.420-432
Hauptverfasser:	Badley, A D, Parato, K, Cameron, D W, Kravcik, S, Phenix, B N, Ashby, D, Kumar, A, Lynch, D H, Tschopp, J, Angel, J B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult AIDS/HIV Anti-HIV Agents - therapeutic use Apoptosis Carrier Proteins - biosynthesis CASP8 and FADD-Like Apoptosis Regulating Protein CD4 antigen CD8 antigen Drug Therapy, Combination fas Receptor - biosynthesis HIV Infections - drug therapy HIV Infections - immunology HIV Infections - virology HIV Protease Inhibitors - therapeutic use Human immunodeficiency virus Humans Intracellular Signaling Peptides and Proteins Middle Aged nelfinavir Nelfinavir - therapeutic use Nucleosides - therapeutic use Reverse Transcriptase Inhibitors - therapeutic use Saquinavir - therapeutic use T-Lymphocytes - immunology
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