Structure‐activity relationships within the N‐terminal short consensus repeats (SCR) of human CR1 (C3b / C4b receptor, CD35): SCR 3 plays a critical role in inhibition of the classical and alternative pathways of complement activation

Genes coding for between one and four short consensus repeats (SCR) of the N‐terminal region of human complement receptor 1 (CR1) were synthesized from oligonucleotides and those encoding SCR(1 – 2), SCR(1 – 3), SCR(1 – 4), SCR3 and SCR(3 – 4) were expressed as inclusion bodies in Escherichia coli....

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