Cervical neurofibromas in children with NF-1
Children with neurofibromatosis type 1 (NF1) are at increased risk of developing plexiform neurofibroma throughout the body, including the cervical soft tissues. However, the incidence of cervical soft tissue tumors and the value of screening MR for children with NF1 are not known. The purposes of t...
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| Veröffentlicht in: | Pediatric radiology 1999-05, Vol.29 (5), p.353-356 |
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| creator | CHUNG, C. J ARMFIELD, K. B MUKHERJI, S. K FORDHAM, L. A KRAUSE, W. L |
| description | Children with neurofibromatosis type 1 (NF1) are at increased risk of developing plexiform neurofibroma throughout the body, including the cervical soft tissues. However, the incidence of cervical soft tissue tumors and the value of screening MR for children with NF1 are not known.
The purposes of this study were to determine the incidence and clinical significance of cervical tumors seen on MR imaging in children with NF1.
A retrospective review of the brain and orbit MR with cervical images obtained on 95 children who meet the NIH consensus criteria for NF1 and who are followed at our neurofibromatosis clinic was carried out.
Cervical tumors were found on MR imaging in 21 of 95 (22%) children. Of 21 children with cervical tumors, 14 children were determined to be surgical candidates. In nine children, MR imaging altered the clinical management by demonstrating tumors for which surgery was indicated, but the tumors were not suspected prior to MR imaging.
Cervical tumors are commonly seen in children with NF1. MR imaging may demonstrate a significant number of tumors that require surgery, but were not suspected prior to MR imaging. |
| doi_str_mv | 10.1007/s002470050605 |
| format | Article |
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The purposes of this study were to determine the incidence and clinical significance of cervical tumors seen on MR imaging in children with NF1.
A retrospective review of the brain and orbit MR with cervical images obtained on 95 children who meet the NIH consensus criteria for NF1 and who are followed at our neurofibromatosis clinic was carried out.
Cervical tumors were found on MR imaging in 21 of 95 (22%) children. Of 21 children with cervical tumors, 14 children were determined to be surgical candidates. In nine children, MR imaging altered the clinical management by demonstrating tumors for which surgery was indicated, but the tumors were not suspected prior to MR imaging.
Cervical tumors are commonly seen in children with NF1. MR imaging may demonstrate a significant number of tumors that require surgery, but were not suspected prior to MR imaging.</description><identifier>ISSN: 0301-0449</identifier><identifier>EISSN: 1432-1998</identifier><identifier>DOI: 10.1007/s002470050605</identifier><identifier>PMID: 10382213</identifier><identifier>CODEN: PDRYA5</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>Adolescent ; Biological and medical sciences ; Brain - pathology ; Child ; Child, Preschool ; Diagnosis, Differential ; Head and Neck Neoplasms - diagnosis ; Head and Neck Neoplasms - surgery ; Humans ; Infant ; Infant, Newborn ; Magnetic Resonance Imaging ; Medical sciences ; Neck - pathology ; Neurofibromatosis 1 - diagnosis ; Neurofibromatosis 1 - surgery ; Neurology ; Neurosurgical Procedures ; Orbit - pathology ; Retrospective Studies ; Tumors of the nervous system. Phacomatoses</subject><ispartof>Pediatric radiology, 1999-05, Vol.29 (5), p.353-356</ispartof><rights>1999 INIST-CNRS</rights><rights>Springer-Verlag Berlin Heidelberg 1999</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c345t-6076f833042626954e96dda6ed25b288553ec40437d5169e3077c18d154c44fb3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,776,780,785,786,23909,23910,25118,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1766231$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10382213$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>CHUNG, C. J</creatorcontrib><creatorcontrib>ARMFIELD, K. B</creatorcontrib><creatorcontrib>MUKHERJI, S. K</creatorcontrib><creatorcontrib>FORDHAM, L. A</creatorcontrib><creatorcontrib>KRAUSE, W. L</creatorcontrib><title>Cervical neurofibromas in children with NF-1</title><title>Pediatric radiology</title><addtitle>Pediatr Radiol</addtitle><description>Children with neurofibromatosis type 1 (NF1) are at increased risk of developing plexiform neurofibroma throughout the body, including the cervical soft tissues. However, the incidence of cervical soft tissue tumors and the value of screening MR for children with NF1 are not known.
The purposes of this study were to determine the incidence and clinical significance of cervical tumors seen on MR imaging in children with NF1.
A retrospective review of the brain and orbit MR with cervical images obtained on 95 children who meet the NIH consensus criteria for NF1 and who are followed at our neurofibromatosis clinic was carried out.
Cervical tumors were found on MR imaging in 21 of 95 (22%) children. Of 21 children with cervical tumors, 14 children were determined to be surgical candidates. In nine children, MR imaging altered the clinical management by demonstrating tumors for which surgery was indicated, but the tumors were not suspected prior to MR imaging.
Cervical tumors are commonly seen in children with NF1. MR imaging may demonstrate a significant number of tumors that require surgery, but were not suspected prior to MR imaging.</description><subject>Adolescent</subject><subject>Biological and medical sciences</subject><subject>Brain - pathology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Diagnosis, Differential</subject><subject>Head and Neck Neoplasms - diagnosis</subject><subject>Head and Neck Neoplasms - surgery</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical sciences</subject><subject>Neck - pathology</subject><subject>Neurofibromatosis 1 - diagnosis</subject><subject>Neurofibromatosis 1 - surgery</subject><subject>Neurology</subject><subject>Neurosurgical Procedures</subject><subject>Orbit - pathology</subject><subject>Retrospective Studies</subject><subject>Tumors of the nervous system. 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J ; ARMFIELD, K. B ; MUKHERJI, S. K ; FORDHAM, L. A ; KRAUSE, W. L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c345t-6076f833042626954e96dda6ed25b288553ec40437d5169e3077c18d154c44fb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adolescent</topic><topic>Biological and medical sciences</topic><topic>Brain - pathology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Diagnosis, Differential</topic><topic>Head and Neck Neoplasms - diagnosis</topic><topic>Head and Neck Neoplasms - surgery</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical sciences</topic><topic>Neck - pathology</topic><topic>Neurofibromatosis 1 - diagnosis</topic><topic>Neurofibromatosis 1 - surgery</topic><topic>Neurology</topic><topic>Neurosurgical Procedures</topic><topic>Orbit - pathology</topic><topic>Retrospective Studies</topic><topic>Tumors of the nervous system. Phacomatoses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>CHUNG, C. J</creatorcontrib><creatorcontrib>ARMFIELD, K. B</creatorcontrib><creatorcontrib>MUKHERJI, S. K</creatorcontrib><creatorcontrib>FORDHAM, L. A</creatorcontrib><creatorcontrib>KRAUSE, W. 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J</au><au>ARMFIELD, K. B</au><au>MUKHERJI, S. K</au><au>FORDHAM, L. A</au><au>KRAUSE, W. L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cervical neurofibromas in children with NF-1</atitle><jtitle>Pediatric radiology</jtitle><addtitle>Pediatr Radiol</addtitle><date>1999-05-01</date><risdate>1999</risdate><volume>29</volume><issue>5</issue><spage>353</spage><epage>356</epage><pages>353-356</pages><issn>0301-0449</issn><eissn>1432-1998</eissn><coden>PDRYA5</coden><abstract>Children with neurofibromatosis type 1 (NF1) are at increased risk of developing plexiform neurofibroma throughout the body, including the cervical soft tissues. However, the incidence of cervical soft tissue tumors and the value of screening MR for children with NF1 are not known.
The purposes of this study were to determine the incidence and clinical significance of cervical tumors seen on MR imaging in children with NF1.
A retrospective review of the brain and orbit MR with cervical images obtained on 95 children who meet the NIH consensus criteria for NF1 and who are followed at our neurofibromatosis clinic was carried out.
Cervical tumors were found on MR imaging in 21 of 95 (22%) children. Of 21 children with cervical tumors, 14 children were determined to be surgical candidates. In nine children, MR imaging altered the clinical management by demonstrating tumors for which surgery was indicated, but the tumors were not suspected prior to MR imaging.
Cervical tumors are commonly seen in children with NF1. MR imaging may demonstrate a significant number of tumors that require surgery, but were not suspected prior to MR imaging.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>10382213</pmid><doi>10.1007/s002470050605</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0301-0449 |
| ispartof | Pediatric radiology, 1999-05, Vol.29 (5), p.353-356 |
| issn | 0301-0449 1432-1998 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adolescent Biological and medical sciences Brain - pathology Child Child, Preschool Diagnosis, Differential Head and Neck Neoplasms - diagnosis Head and Neck Neoplasms - surgery Humans Infant Infant, Newborn Magnetic Resonance Imaging Medical sciences Neck - pathology Neurofibromatosis 1 - diagnosis Neurofibromatosis 1 - surgery Neurology Neurosurgical Procedures Orbit - pathology Retrospective Studies Tumors of the nervous system. Phacomatoses |
| title | Cervical neurofibromas in children with NF-1 |
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