Laboratory testing for fibrinogen abnormalities
Fibrinogen is essential for the formation of a fibrin clot. Acquired and congenital disorders of fibrinogen may result in decreased concentration or altered function of fibrinogen, often leading to an increased risk of bleeding. Routine coagulation testing and specialized laboratory investigations c...
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Veröffentlicht in: | American journal of hematology 2008-12, Vol.83 (12), p.928-931 |
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container_title | American journal of hematology |
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creator | Verhovsek, Madeleine Moffat, Karen A. Hayward, Catherine P.M. |
description | Fibrinogen is essential for the formation of a fibrin clot. Acquired and congenital disorders of fibrinogen may result in decreased concentration or altered function of fibrinogen, often leading to an increased risk of bleeding. Routine coagulation testing and specialized laboratory investigations can guide diagnosis in patients suspected of having a fibrinogen abnormality. This article summarizes the types of laboratory assays that are used to assess fibrinogen disorders, and key abnormalities found in different types of fibrinogen disorders.disorders. Am. J. Hematol., 2008. © 2008 Wiley‐Liss, Inc. |
doi_str_mv | 10.1002/ajh.21293 |
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Acquired and congenital disorders of fibrinogen may result in decreased concentration or altered function of fibrinogen, often leading to an increased risk of bleeding. Routine coagulation testing and specialized laboratory investigations can guide diagnosis in patients suspected of having a fibrinogen abnormality. This article summarizes the types of laboratory assays that are used to assess fibrinogen disorders, and key abnormalities found in different types of fibrinogen disorders.disorders. Am. J. 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Acquired and congenital disorders of fibrinogen may result in decreased concentration or altered function of fibrinogen, often leading to an increased risk of bleeding. Routine coagulation testing and specialized laboratory investigations can guide diagnosis in patients suspected of having a fibrinogen abnormality. This article summarizes the types of laboratory assays that are used to assess fibrinogen disorders, and key abnormalities found in different types of fibrinogen disorders.disorders. Am. J. Hematol., 2008. © 2008 Wiley‐Liss, Inc.</description><subject>Afibrinogenemia - blood</subject><subject>Afibrinogenemia - diagnosis</subject><subject>Biological and medical sciences</subject><subject>Blood Coagulation Tests</subject><subject>Fibrinogens, Abnormal - isolation & purification</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Medical sciences</subject><issn>0361-8609</issn><issn>1096-8652</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10L1OwzAUBWALgWgpDLwAygISQ1r_JI49ogooqBILzJbt2MVVEhc7FerbY0gEE9O9w6dzrw4AlwjOEYR4Ibfvc4wwJ0dgiiCnOaMlPgZTSChKO-QTcBbjFkKECgZPwQQxXqKC0ilYrKXyQfY-HLLexN51m8z6kFmnguv8xnSZVJ0PrWxc70w8BydWNtFcjHMG3h7uX5erfP3y-LS8W-e6QJzkBSyUJQaX2la1Lhnk3FheSaWVIaayCDNDq5oRXGBFlbTWspojrZWscRpkBm6G3F3wH_v0mGhd1KZpZGf8PgrKGUFVBRO8HaAOPsZgrNgF18pwEAiK73ZEakf8tJPs1Ri6V62p_-RYRwLXI5BRy8YG2WkXfx2GrCIEouQWg_t0jTn8f1HcPa-G018gH3vd</recordid><startdate>200812</startdate><enddate>200812</enddate><creator>Verhovsek, Madeleine</creator><creator>Moffat, Karen A.</creator><creator>Hayward, Catherine P.M.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200812</creationdate><title>Laboratory testing for fibrinogen abnormalities</title><author>Verhovsek, Madeleine ; Moffat, Karen A. ; Hayward, Catherine P.M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4193-404bf3e25cf7dc58099ef97abcbe3e7f128e67d83242b6bafff8d91ccbad21cc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Afibrinogenemia - blood</topic><topic>Afibrinogenemia - diagnosis</topic><topic>Biological and medical sciences</topic><topic>Blood Coagulation Tests</topic><topic>Fibrinogens, Abnormal - isolation & purification</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Medical sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Verhovsek, Madeleine</creatorcontrib><creatorcontrib>Moffat, Karen A.</creatorcontrib><creatorcontrib>Hayward, Catherine P.M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of hematology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Verhovsek, Madeleine</au><au>Moffat, Karen A.</au><au>Hayward, Catherine P.M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Laboratory testing for fibrinogen abnormalities</atitle><jtitle>American journal of hematology</jtitle><addtitle>Am J Hematol</addtitle><date>2008-12</date><risdate>2008</risdate><volume>83</volume><issue>12</issue><spage>928</spage><epage>931</epage><pages>928-931</pages><issn>0361-8609</issn><eissn>1096-8652</eissn><coden>AJHEDD</coden><abstract>Fibrinogen is essential for the formation of a fibrin clot. 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subjects | Afibrinogenemia - blood Afibrinogenemia - diagnosis Biological and medical sciences Blood Coagulation Tests Fibrinogens, Abnormal - isolation & purification Hematologic and hematopoietic diseases Humans Medical sciences |
title | Laboratory testing for fibrinogen abnormalities |
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