Laboratory testing for fibrinogen abnormalities

Fibrinogen is essential for the formation of a fibrin clot. Acquired and congenital disorders of fibrinogen may result in decreased concentration or altered function of fibrinogen, often leading to an increased risk of bleeding. Routine coagulation testing and specialized laboratory investigations c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:American journal of hematology 2008-12, Vol.83 (12), p.928-931
Hauptverfasser: Verhovsek, Madeleine, Moffat, Karen A., Hayward, Catherine P.M.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 931
container_issue 12
container_start_page 928
container_title American journal of hematology
container_volume 83
creator Verhovsek, Madeleine
Moffat, Karen A.
Hayward, Catherine P.M.
description Fibrinogen is essential for the formation of a fibrin clot. Acquired and congenital disorders of fibrinogen may result in decreased concentration or altered function of fibrinogen, often leading to an increased risk of bleeding. Routine coagulation testing and specialized laboratory investigations can guide diagnosis in patients suspected of having a fibrinogen abnormality. This article summarizes the types of laboratory assays that are used to assess fibrinogen disorders, and key abnormalities found in different types of fibrinogen disorders.disorders. Am. J. Hematol., 2008. © 2008 Wiley‐Liss, Inc.
doi_str_mv 10.1002/ajh.21293
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69831770</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69831770</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4193-404bf3e25cf7dc58099ef97abcbe3e7f128e67d83242b6bafff8d91ccbad21cc3</originalsourceid><addsrcrecordid>eNp10L1OwzAUBWALgWgpDLwAygISQ1r_JI49ogooqBILzJbt2MVVEhc7FerbY0gEE9O9w6dzrw4AlwjOEYR4Ibfvc4wwJ0dgiiCnOaMlPgZTSChKO-QTcBbjFkKECgZPwQQxXqKC0ilYrKXyQfY-HLLexN51m8z6kFmnguv8xnSZVJ0PrWxc70w8BydWNtFcjHMG3h7uX5erfP3y-LS8W-e6QJzkBSyUJQaX2la1Lhnk3FheSaWVIaayCDNDq5oRXGBFlbTWspojrZWscRpkBm6G3F3wH_v0mGhd1KZpZGf8PgrKGUFVBRO8HaAOPsZgrNgF18pwEAiK73ZEakf8tJPs1Ri6V62p_-RYRwLXI5BRy8YG2WkXfx2GrCIEouQWg_t0jTn8f1HcPa-G018gH3vd</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69831770</pqid></control><display><type>article</type><title>Laboratory testing for fibrinogen abnormalities</title><source>Wiley Free Content</source><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Verhovsek, Madeleine ; Moffat, Karen A. ; Hayward, Catherine P.M.</creator><creatorcontrib>Verhovsek, Madeleine ; Moffat, Karen A. ; Hayward, Catherine P.M.</creatorcontrib><description>Fibrinogen is essential for the formation of a fibrin clot. Acquired and congenital disorders of fibrinogen may result in decreased concentration or altered function of fibrinogen, often leading to an increased risk of bleeding. Routine coagulation testing and specialized laboratory investigations can guide diagnosis in patients suspected of having a fibrinogen abnormality. This article summarizes the types of laboratory assays that are used to assess fibrinogen disorders, and key abnormalities found in different types of fibrinogen disorders.disorders. Am. J. Hematol., 2008. © 2008 Wiley‐Liss, Inc.</description><identifier>ISSN: 0361-8609</identifier><identifier>EISSN: 1096-8652</identifier><identifier>DOI: 10.1002/ajh.21293</identifier><identifier>PMID: 18951466</identifier><identifier>CODEN: AJHEDD</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Afibrinogenemia - blood ; Afibrinogenemia - diagnosis ; Biological and medical sciences ; Blood Coagulation Tests ; Fibrinogens, Abnormal - isolation &amp; purification ; Hematologic and hematopoietic diseases ; Humans ; Medical sciences</subject><ispartof>American journal of hematology, 2008-12, Vol.83 (12), p.928-931</ispartof><rights>Copyright © 2008 Wiley‐Liss, Inc.</rights><rights>2009 INIST-CNRS</rights><rights>Copyright 2008 Wiley-Liss, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4193-404bf3e25cf7dc58099ef97abcbe3e7f128e67d83242b6bafff8d91ccbad21cc3</citedby><cites>FETCH-LOGICAL-c4193-404bf3e25cf7dc58099ef97abcbe3e7f128e67d83242b6bafff8d91ccbad21cc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fajh.21293$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fajh.21293$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,1427,27901,27902,45550,45551,46384,46808</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=20873301$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18951466$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Verhovsek, Madeleine</creatorcontrib><creatorcontrib>Moffat, Karen A.</creatorcontrib><creatorcontrib>Hayward, Catherine P.M.</creatorcontrib><title>Laboratory testing for fibrinogen abnormalities</title><title>American journal of hematology</title><addtitle>Am J Hematol</addtitle><description>Fibrinogen is essential for the formation of a fibrin clot. Acquired and congenital disorders of fibrinogen may result in decreased concentration or altered function of fibrinogen, often leading to an increased risk of bleeding. Routine coagulation testing and specialized laboratory investigations can guide diagnosis in patients suspected of having a fibrinogen abnormality. This article summarizes the types of laboratory assays that are used to assess fibrinogen disorders, and key abnormalities found in different types of fibrinogen disorders.disorders. Am. J. Hematol., 2008. © 2008 Wiley‐Liss, Inc.</description><subject>Afibrinogenemia - blood</subject><subject>Afibrinogenemia - diagnosis</subject><subject>Biological and medical sciences</subject><subject>Blood Coagulation Tests</subject><subject>Fibrinogens, Abnormal - isolation &amp; purification</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Medical sciences</subject><issn>0361-8609</issn><issn>1096-8652</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10L1OwzAUBWALgWgpDLwAygISQ1r_JI49ogooqBILzJbt2MVVEhc7FerbY0gEE9O9w6dzrw4AlwjOEYR4Ibfvc4wwJ0dgiiCnOaMlPgZTSChKO-QTcBbjFkKECgZPwQQxXqKC0ilYrKXyQfY-HLLexN51m8z6kFmnguv8xnSZVJ0PrWxc70w8BydWNtFcjHMG3h7uX5erfP3y-LS8W-e6QJzkBSyUJQaX2la1Lhnk3FheSaWVIaayCDNDq5oRXGBFlbTWspojrZWscRpkBm6G3F3wH_v0mGhd1KZpZGf8PgrKGUFVBRO8HaAOPsZgrNgF18pwEAiK73ZEakf8tJPs1Ri6V62p_-RYRwLXI5BRy8YG2WkXfx2GrCIEouQWg_t0jTn8f1HcPa-G018gH3vd</recordid><startdate>200812</startdate><enddate>200812</enddate><creator>Verhovsek, Madeleine</creator><creator>Moffat, Karen A.</creator><creator>Hayward, Catherine P.M.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200812</creationdate><title>Laboratory testing for fibrinogen abnormalities</title><author>Verhovsek, Madeleine ; Moffat, Karen A. ; Hayward, Catherine P.M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4193-404bf3e25cf7dc58099ef97abcbe3e7f128e67d83242b6bafff8d91ccbad21cc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Afibrinogenemia - blood</topic><topic>Afibrinogenemia - diagnosis</topic><topic>Biological and medical sciences</topic><topic>Blood Coagulation Tests</topic><topic>Fibrinogens, Abnormal - isolation &amp; purification</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Medical sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Verhovsek, Madeleine</creatorcontrib><creatorcontrib>Moffat, Karen A.</creatorcontrib><creatorcontrib>Hayward, Catherine P.M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of hematology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Verhovsek, Madeleine</au><au>Moffat, Karen A.</au><au>Hayward, Catherine P.M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Laboratory testing for fibrinogen abnormalities</atitle><jtitle>American journal of hematology</jtitle><addtitle>Am J Hematol</addtitle><date>2008-12</date><risdate>2008</risdate><volume>83</volume><issue>12</issue><spage>928</spage><epage>931</epage><pages>928-931</pages><issn>0361-8609</issn><eissn>1096-8652</eissn><coden>AJHEDD</coden><abstract>Fibrinogen is essential for the formation of a fibrin clot. Acquired and congenital disorders of fibrinogen may result in decreased concentration or altered function of fibrinogen, often leading to an increased risk of bleeding. Routine coagulation testing and specialized laboratory investigations can guide diagnosis in patients suspected of having a fibrinogen abnormality. This article summarizes the types of laboratory assays that are used to assess fibrinogen disorders, and key abnormalities found in different types of fibrinogen disorders.disorders. Am. J. Hematol., 2008. © 2008 Wiley‐Liss, Inc.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>18951466</pmid><doi>10.1002/ajh.21293</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0361-8609
ispartof American journal of hematology, 2008-12, Vol.83 (12), p.928-931
issn 0361-8609
1096-8652
language eng
recordid cdi_proquest_miscellaneous_69831770
source Wiley Free Content; MEDLINE; Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Afibrinogenemia - blood
Afibrinogenemia - diagnosis
Biological and medical sciences
Blood Coagulation Tests
Fibrinogens, Abnormal - isolation & purification
Hematologic and hematopoietic diseases
Humans
Medical sciences
title Laboratory testing for fibrinogen abnormalities
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T05%3A35%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Laboratory%20testing%20for%20fibrinogen%20abnormalities&rft.jtitle=American%20journal%20of%20hematology&rft.au=Verhovsek,%20Madeleine&rft.date=2008-12&rft.volume=83&rft.issue=12&rft.spage=928&rft.epage=931&rft.pages=928-931&rft.issn=0361-8609&rft.eissn=1096-8652&rft.coden=AJHEDD&rft_id=info:doi/10.1002/ajh.21293&rft_dat=%3Cproquest_cross%3E69831770%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=69831770&rft_id=info:pmid/18951466&rfr_iscdi=true