SiRNA inhibition of ER-alpha expression reduces KGF-induced proliferation of breast cancer cells

Keratinocyte growth factor (KGF) produces a rapid increase in the proliferation and motility of estrogen receptor (ER)-positive breast cancer cells which is abolished by estrogen deprivation and/or anti-estrogen treatment. The present study examined the hypothesis that ER-alpha is involved in the KG...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Anticancer research 2008-09, Vol.28 (5A), p.2733-2735
Hauptverfasser:	Zang, Xiao-Ping, Pento, J Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Cell Growth Processes - drug effects Cell Growth Processes - genetics Cell Line, Tumor Estrogen Receptor alpha - antagonists & inhibitors Estrogen Receptor alpha - biosynthesis Estrogen Receptor alpha - genetics Fibroblast Growth Factor 7 - antagonists & inhibitors Fibroblast Growth Factor 7 - pharmacology Humans RNA, Small Interfering - genetics Transfection
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!