Depression, disease severity, and Sickle cell disease
The present study examined depressive symptomatology in 440 adults with sickle cell disease (SCD). Participants completed the Center for Epidemiologic Studies--Depression scale (CES-D) as part of their yearly routine visits to the Duke University--University of North Carolina Comprehensive Sickle Ce...
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| Veröffentlicht in: | Journal of behavioral medicine 1999-04, Vol.22 (2), p.115-126 |
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| container_title | Journal of behavioral medicine |
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| creator | SCHAEFFER, J. J. W GIL, K. M BURCHINAL, M KRAMER, K. D NASH, K. B ORRINGER, E STRAYHORN, D |
| description | The present study examined depressive symptomatology in 440 adults with sickle cell disease (SCD). Participants completed the Center for Epidemiologic Studies--Depression scale (CES-D) as part of their yearly routine visits to the Duke University--University of North Carolina Comprehensive Sickle Cell Center. They also completed questions regarding demographics, disease severity, pain, and health care use. Data analyses revealed that the percentage of patients with SCD exhibiting significant depressive symptomatology dropped from 43 to 18% when a more stringent cutoff was used on the CES-D, suggesting that future studies should determine the most valid cutoff score for identifying depression in patients with SCD. Gender and family income were positively and significantly associated with depressive symptomatology. Also, patients who reported more frequent painful episodes were more likely to report depressive symptoms. Implications for assessment and treatment of depression in adults with SCD are discussed. |
| doi_str_mv | 10.1023/A:1018755831101 |
| format | Article |
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J. W ; GIL, K. M ; BURCHINAL, M ; KRAMER, K. D ; NASH, K. B ; ORRINGER, E ; STRAYHORN, D</creator><creatorcontrib>SCHAEFFER, J. J. W ; GIL, K. M ; BURCHINAL, M ; KRAMER, K. D ; NASH, K. B ; ORRINGER, E ; STRAYHORN, D</creatorcontrib><description>The present study examined depressive symptomatology in 440 adults with sickle cell disease (SCD). Participants completed the Center for Epidemiologic Studies--Depression scale (CES-D) as part of their yearly routine visits to the Duke University--University of North Carolina Comprehensive Sickle Cell Center. They also completed questions regarding demographics, disease severity, pain, and health care use. Data analyses revealed that the percentage of patients with SCD exhibiting significant depressive symptomatology dropped from 43 to 18% when a more stringent cutoff was used on the CES-D, suggesting that future studies should determine the most valid cutoff score for identifying depression in patients with SCD. Gender and family income were positively and significantly associated with depressive symptomatology. Also, patients who reported more frequent painful episodes were more likely to report depressive symptoms. Implications for assessment and treatment of depression in adults with SCD are discussed.</description><identifier>ISSN: 0160-7715</identifier><identifier>EISSN: 1573-3521</identifier><identifier>DOI: 10.1023/A:1018755831101</identifier><identifier>PMID: 10374138</identifier><identifier>CODEN: JBMEDD</identifier><language>eng</language><publisher>New York, NY: Springer</publisher><subject>Adult ; Adult and adolescent clinical studies ; Anemia, Sickle Cell - epidemiology ; Anemia, Sickle Cell - psychology ; Anemias. Hemoglobinopathies ; Biological and medical sciences ; Chi-Square Distribution ; Chronic illnesses ; Comorbidity ; Depression ; Depression - epidemiology ; Diseases of red blood cells ; Family income ; Female ; Health Surveys ; Hematologic and hematopoietic diseases ; Humans ; Male ; Medical sciences ; Mental depression ; Mood disorders ; Odds Ratio ; Pain ; Pain - ethnology ; Pain - psychology ; Psychiatric Status Rating Scales - standards ; Psychology. Psychoanalysis. Psychiatry ; Psychometrics ; Psychopathology. Psychiatry ; Regression Analysis ; Risk Factors ; Sampling Studies ; Self Disclosure ; Sensitivity and Specificity ; Severity of Illness Index ; Sex Distribution ; Sex Factors ; Sickle cell disease ; Socioeconomic Factors</subject><ispartof>Journal of behavioral medicine, 1999-04, Vol.22 (2), p.115-126</ispartof><rights>1999 INIST-CNRS</rights><rights>Plenum Publishing Corporation 1999</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c355t-cfe8fdf5f2d96968009c8f3a07eea5833680ad99683ae6c2d988cbf985eb97103</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,12846,27924,27925,30999</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1847996$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10374138$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SCHAEFFER, J. J. W</creatorcontrib><creatorcontrib>GIL, K. M</creatorcontrib><creatorcontrib>BURCHINAL, M</creatorcontrib><creatorcontrib>KRAMER, K. D</creatorcontrib><creatorcontrib>NASH, K. B</creatorcontrib><creatorcontrib>ORRINGER, E</creatorcontrib><creatorcontrib>STRAYHORN, D</creatorcontrib><title>Depression, disease severity, and Sickle cell disease</title><title>Journal of behavioral medicine</title><addtitle>J Behav Med</addtitle><description>The present study examined depressive symptomatology in 440 adults with sickle cell disease (SCD). Participants completed the Center for Epidemiologic Studies--Depression scale (CES-D) as part of their yearly routine visits to the Duke University--University of North Carolina Comprehensive Sickle Cell Center. They also completed questions regarding demographics, disease severity, pain, and health care use. Data analyses revealed that the percentage of patients with SCD exhibiting significant depressive symptomatology dropped from 43 to 18% when a more stringent cutoff was used on the CES-D, suggesting that future studies should determine the most valid cutoff score for identifying depression in patients with SCD. Gender and family income were positively and significantly associated with depressive symptomatology. Also, patients who reported more frequent painful episodes were more likely to report depressive symptoms. Implications for assessment and treatment of depression in adults with SCD are discussed.</description><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Anemia, Sickle Cell - epidemiology</subject><subject>Anemia, Sickle Cell - psychology</subject><subject>Anemias. Hemoglobinopathies</subject><subject>Biological and medical sciences</subject><subject>Chi-Square Distribution</subject><subject>Chronic illnesses</subject><subject>Comorbidity</subject><subject>Depression</subject><subject>Depression - epidemiology</subject><subject>Diseases of red blood cells</subject><subject>Family income</subject><subject>Female</subject><subject>Health Surveys</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mental depression</subject><subject>Mood disorders</subject><subject>Odds Ratio</subject><subject>Pain</subject><subject>Pain - ethnology</subject><subject>Pain - psychology</subject><subject>Psychiatric Status Rating Scales - standards</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychometrics</subject><subject>Psychopathology. Psychiatry</subject><subject>Regression Analysis</subject><subject>Risk Factors</subject><subject>Sampling Studies</subject><subject>Self Disclosure</subject><subject>Sensitivity and Specificity</subject><subject>Severity of Illness Index</subject><subject>Sex Distribution</subject><subject>Sex Factors</subject><subject>Sickle cell disease</subject><subject>Socioeconomic Factors</subject><issn>0160-7715</issn><issn>1573-3521</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpd0ElLAzEUwPEgiq3VszcZRDx1NMtk663UFQoe1POQybxA6iw16Qj99kZsETwlvPx4_AlC5wTfEEzZ7XxGMFGSc8VIuh2gMeGS5YxTcojGmAicS0n4CJ3EuMIYC13oYzQimMmCMDVG_A7WAWL0fTfNah_BRMgifEHwm-00M12dvXr70UBmoWn24hQdOdNEONudE_T-cP-2eMqXL4_Pi_kyt4zzTW4dKFc77mithRYKY22VYwZLAJOSWRqZWqcXZkDYpJSyldOKQ6Vlipyg69-969B_DhA3ZevjT4jpoB9iKbSiijCa4OU_uOqH0KW2kjIiCymoSuhih4aqhbpcB9-asC33v5HA1Q6YaE3jgumsj39OFTLFsm9FU2vz</recordid><startdate>19990401</startdate><enddate>19990401</enddate><creator>SCHAEFFER, J. 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Hemoglobinopathies</topic><topic>Biological and medical sciences</topic><topic>Chi-Square Distribution</topic><topic>Chronic illnesses</topic><topic>Comorbidity</topic><topic>Depression</topic><topic>Depression - epidemiology</topic><topic>Diseases of red blood cells</topic><topic>Family income</topic><topic>Female</topic><topic>Health Surveys</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mental depression</topic><topic>Mood disorders</topic><topic>Odds Ratio</topic><topic>Pain</topic><topic>Pain - ethnology</topic><topic>Pain - psychology</topic><topic>Psychiatric Status Rating Scales - standards</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychometrics</topic><topic>Psychopathology. Psychiatry</topic><topic>Regression Analysis</topic><topic>Risk Factors</topic><topic>Sampling Studies</topic><topic>Self Disclosure</topic><topic>Sensitivity and Specificity</topic><topic>Severity of Illness Index</topic><topic>Sex Distribution</topic><topic>Sex Factors</topic><topic>Sickle cell disease</topic><topic>Socioeconomic Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SCHAEFFER, J. J. W</creatorcontrib><creatorcontrib>GIL, K. M</creatorcontrib><creatorcontrib>BURCHINAL, M</creatorcontrib><creatorcontrib>KRAMER, K. D</creatorcontrib><creatorcontrib>NASH, K. 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J. W</au><au>GIL, K. M</au><au>BURCHINAL, M</au><au>KRAMER, K. D</au><au>NASH, K. B</au><au>ORRINGER, E</au><au>STRAYHORN, D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Depression, disease severity, and Sickle cell disease</atitle><jtitle>Journal of behavioral medicine</jtitle><addtitle>J Behav Med</addtitle><date>1999-04-01</date><risdate>1999</risdate><volume>22</volume><issue>2</issue><spage>115</spage><epage>126</epage><pages>115-126</pages><issn>0160-7715</issn><eissn>1573-3521</eissn><coden>JBMEDD</coden><abstract>The present study examined depressive symptomatology in 440 adults with sickle cell disease (SCD). Participants completed the Center for Epidemiologic Studies--Depression scale (CES-D) as part of their yearly routine visits to the Duke University--University of North Carolina Comprehensive Sickle Cell Center. They also completed questions regarding demographics, disease severity, pain, and health care use. Data analyses revealed that the percentage of patients with SCD exhibiting significant depressive symptomatology dropped from 43 to 18% when a more stringent cutoff was used on the CES-D, suggesting that future studies should determine the most valid cutoff score for identifying depression in patients with SCD. Gender and family income were positively and significantly associated with depressive symptomatology. Also, patients who reported more frequent painful episodes were more likely to report depressive symptoms. Implications for assessment and treatment of depression in adults with SCD are discussed.</abstract><cop>New York, NY</cop><pub>Springer</pub><pmid>10374138</pmid><doi>10.1023/A:1018755831101</doi><tpages>12</tpages></addata></record> |
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| source | MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); SpringerLink Journals - AutoHoldings |
| subjects | Adult Adult and adolescent clinical studies Anemia, Sickle Cell - epidemiology Anemia, Sickle Cell - psychology Anemias. Hemoglobinopathies Biological and medical sciences Chi-Square Distribution Chronic illnesses Comorbidity Depression Depression - epidemiology Diseases of red blood cells Family income Female Health Surveys Hematologic and hematopoietic diseases Humans Male Medical sciences Mental depression Mood disorders Odds Ratio Pain Pain - ethnology Pain - psychology Psychiatric Status Rating Scales - standards Psychology. Psychoanalysis. Psychiatry Psychometrics Psychopathology. Psychiatry Regression Analysis Risk Factors Sampling Studies Self Disclosure Sensitivity and Specificity Severity of Illness Index Sex Distribution Sex Factors Sickle cell disease Socioeconomic Factors |
| title | Depression, disease severity, and Sickle cell disease |
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