Astrogliosis and the ApoE genotype: An immunohistochemical study of postmortem human brain tissue

Significantly increased glial fibrillary acidic protein (GFAP) expression was seen in postmortem brain tissue from demented patients with Alzheimer's disease (AD) (73 cases, 61 females/12 males, mean age 84 +/- 9 years) compared to controls (22 cases, 10 females/12 males, mean age 78 +/- 9 year...

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Veröffentlicht in:	Dementia and geriatric cognitive disorders 1999-07, Vol.10 (4), p.252-257
Hauptverfasser:	OVERMYER, M, HELISALMI, S, SOININEN, H, LAAKSO, M, RIEKKINEN, P. SR, ALAFUZOFF, I
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Aging - pathology Alzheimer Disease - pathology Apolipoprotein E4 Apolipoproteins E - genetics Apolipoproteins E - metabolism Astrocytes - pathology Biological and medical sciences Brain - cytology Brain - pathology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Genotype Glial Fibrillary Acidic Protein - analysis Gliosis - pathology Humans Immunohistochemistry In Vitro Techniques Male Medical sciences Neurofibrillary Tangles - pathology Neurology Plaque, Amyloid - pathology Regression Analysis
Online-Zugang:	Volltext
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