Keratin 19 Downregulation by Oral Squamous Cell Carcinoma Lines Increases Invasive Potential

Squamous cell carcinoma (SCC) of the head and neck is the sixth most frequent cancer worldwide. The survival rate is among the lowest of the major cancers and has not improved significantly in the past two decades. Extensive local invasion and regional lymph node metastasis are, in large part, respo...

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Veröffentlicht in:	Journal of dental research 1999-06, Vol.78 (6), p.1256-1263
Hauptverfasser:	Crowe, D.L., Milo, G.E., Shuler, C.E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Basement Membrane - pathology Blotting, Western Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - secondary Cell Adhesion - genetics Cell Line, Transformed Cell Movement - genetics Coloring Agents Dentistry DNA, Complementary - genetics Down-Regulation Electrophoresis, Polyacrylamide Gel Epithelial Cells - pathology Fluorescent Antibody Technique Gene Expression Regulation, Enzymologic Gene Expression Regulation, Neoplastic Humans Immunohistochemistry Intermediate Filament Proteins - genetics Keratins - genetics Lymphatic Metastasis - pathology Metalloendopeptidases - genetics Mouth Mucosa - pathology Mouth Neoplasms - genetics Mouth Neoplasms - pathology Neoplasm Invasiveness Prognosis Survival Rate Tumor Cells, Cultured
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