Backward masking in bipolar affective disorder

1. 1. When an informational stimulus, the target, is followed closely in time by a noninformational stimulus, the mask, the visual system's processing of the informational stimulus is disturbed. This disturbance is known as backward visual masking. 2. 2. Transient and sustained visual pathways...

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Veröffentlicht in:Progress in Neuropsychopharmacology & Biological Psychiatry 1999-02, Vol.23 (2), p.195-206
1. Verfasser: Mcclure, Robert K.
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description 1. 1. When an informational stimulus, the target, is followed closely in time by a noninformational stimulus, the mask, the visual system's processing of the informational stimulus is disturbed. This disturbance is known as backward visual masking. 2. 2. Transient and sustained visual pathways detect different characteristics of a visual stimulus, at different times in early visual information processing, and have unique anatomic distribution with regard to retinal origin, thalamic and cortical projections. 3. 3. Backward masking occurs by two mechanisms. Interruption occurs when activity in the transient channels of the mask disrupt activity in the sustained channels of the target. Integration occurs when activity in the sustained channels of the mask disrupt activity of the sustained channels of the target. 4. 4. Characteristics of the mask—energy, location, or the time presented after the target— can be altered to enhance interruption or integration. Interruption is a bell-shaped function of, and integration is an exponential function of, visual performance and interstimulus interval. 5. 5. An impairment in backward masking is present in bipolar subjects during manic episodes, is not related to the presence of psychotic symptoms, and persists when mania resolves. Lithium appears to have a detrimental effect on backward masking.
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When an informational stimulus, the target, is followed closely in time by a noninformational stimulus, the mask, the visual system's processing of the informational stimulus is disturbed. This disturbance is known as backward visual masking. 2. 2. Transient and sustained visual pathways detect different characteristics of a visual stimulus, at different times in early visual information processing, and have unique anatomic distribution with regard to retinal origin, thalamic and cortical projections. 3. 3. Backward masking occurs by two mechanisms. Interruption occurs when activity in the transient channels of the mask disrupt activity in the sustained channels of the target. Integration occurs when activity in the sustained channels of the mask disrupt activity of the sustained channels of the target. 4. 4. Characteristics of the mask—energy, location, or the time presented after the target— can be altered to enhance interruption or integration. Interruption is a bell-shaped function of, and integration is an exponential function of, visual performance and interstimulus interval. 5. 5. An impairment in backward masking is present in bipolar subjects during manic episodes, is not related to the presence of psychotic symptoms, and persists when mania resolves. 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When an informational stimulus, the target, is followed closely in time by a noninformational stimulus, the mask, the visual system's processing of the informational stimulus is disturbed. This disturbance is known as backward visual masking. 2. 2. Transient and sustained visual pathways detect different characteristics of a visual stimulus, at different times in early visual information processing, and have unique anatomic distribution with regard to retinal origin, thalamic and cortical projections. 3. 3. Backward masking occurs by two mechanisms. Interruption occurs when activity in the transient channels of the mask disrupt activity in the sustained channels of the target. Integration occurs when activity in the sustained channels of the mask disrupt activity of the sustained channels of the target. 4. 4. Characteristics of the mask—energy, location, or the time presented after the target— can be altered to enhance interruption or integration. Interruption is a bell-shaped function of, and integration is an exponential function of, visual performance and interstimulus interval. 5. 5. An impairment in backward masking is present in bipolar subjects during manic episodes, is not related to the presence of psychotic symptoms, and persists when mania resolves. Lithium appears to have a detrimental effect on backward masking.</description><subject>Adult and adolescent clinical studies</subject><subject>backward masking</subject><subject>Biological and medical sciences</subject><subject>bipolar affective disorder</subject><subject>bipolar disorder</subject><subject>Bipolar Disorder - physiopathology</subject><subject>Bipolar disorders</subject><subject>cognitive deficits</subject><subject>Drug toxicity and drugs side effects treatment</subject><subject>Humans</subject><subject>Lithium - pharmacology</subject><subject>Medical sciences</subject><subject>Miscellaneous (drug allergy, mutagens, teratogens...)</subject><subject>Mood disorders</subject><subject>Perceptual Masking</subject><subject>Pharmacology. Drug treatments</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. 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Drug treatments</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>psychotic disorders</topic><topic>Psychotic Disorders - physiopathology</topic><topic>visual channels</topic><topic>Visual Pathways - physiopathology</topic><topic>visual perception</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mcclure, Robert K.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Progress in Neuropsychopharmacology &amp; Biological Psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mcclure, Robert K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Backward masking in bipolar affective disorder</atitle><jtitle>Progress in Neuropsychopharmacology &amp; Biological Psychiatry</jtitle><addtitle>Prog Neuropsychopharmacol Biol Psychiatry</addtitle><date>1999-02-01</date><risdate>1999</risdate><volume>23</volume><issue>2</issue><spage>195</spage><epage>206</epage><pages>195-206</pages><issn>0278-5846</issn><eissn>1878-4216</eissn><coden>PNPPD7</coden><abstract>1. 1. When an informational stimulus, the target, is followed closely in time by a noninformational stimulus, the mask, the visual system's processing of the informational stimulus is disturbed. This disturbance is known as backward visual masking. 2. 2. Transient and sustained visual pathways detect different characteristics of a visual stimulus, at different times in early visual information processing, and have unique anatomic distribution with regard to retinal origin, thalamic and cortical projections. 3. 3. Backward masking occurs by two mechanisms. Interruption occurs when activity in the transient channels of the mask disrupt activity in the sustained channels of the target. Integration occurs when activity in the sustained channels of the mask disrupt activity of the sustained channels of the target. 4. 4. Characteristics of the mask—energy, location, or the time presented after the target— can be altered to enhance interruption or integration. Interruption is a bell-shaped function of, and integration is an exponential function of, visual performance and interstimulus interval. 5. 5. An impairment in backward masking is present in bipolar subjects during manic episodes, is not related to the presence of psychotic symptoms, and persists when mania resolves. Lithium appears to have a detrimental effect on backward masking.</abstract><cop>Amsterdam</cop><pub>Elsevier Inc</pub><pmid>10368864</pmid><doi>10.1016/S0278-5846(98)00105-5</doi><tpages>12</tpages></addata></record>
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subjects Adult and adolescent clinical studies
backward masking
Biological and medical sciences
bipolar affective disorder
bipolar disorder
Bipolar Disorder - physiopathology
Bipolar disorders
cognitive deficits
Drug toxicity and drugs side effects treatment
Humans
Lithium - pharmacology
Medical sciences
Miscellaneous (drug allergy, mutagens, teratogens...)
Mood disorders
Perceptual Masking
Pharmacology. Drug treatments
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
psychotic disorders
Psychotic Disorders - physiopathology
visual channels
Visual Pathways - physiopathology
visual perception
title Backward masking in bipolar affective disorder
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