Molecular Cloning, Enzymatic Characterization, Developmental Expression, and Cellular Localization of a Mouse Cytochrome P450 Highly Expressed in Kidney

A cDNA encoding a new cytochrome P450 was isolated from a mouse liver library. Sequence analysis reveals that this 1,886-base pair cDNA encodes a 501-amino acid polypeptide that is 69â74% identical to CYP2J subfamily P450s and is designated CYP2J5. Recombinant CYP2J5 was co-expressed with NADPH-cy...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 1999-06, Vol.274 (25), p.17777-17788
Hauptverfasser:	Ma, J, Qu, W, Scarborough, P E, Tomer, K B, Moomaw, C R, Maronpot, R, Davis, L S, Breyer, M D, Zeldin, D C
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Arachidonic Acid - metabolism Base Sequence Cloning, Molecular Cytochrome P-450 Enzyme System - chemistry Cytochrome P-450 Enzyme System - genetics Eicosanoids - analysis Epoxy Compounds - metabolism Gene Expression Regulation, Developmental Humans Immunohistochemistry In Situ Hybridization Kidney - enzymology Kinetics Mice Molecular Sequence Data NADH, NADPH Oxidoreductases - metabolism NADPH-Ferrihemoprotein Reductase Rats Recombinant Proteins RNA, Messenger - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!