African swine fever virus prenyltransferase is an integral membrane trans-geranylgeranyl-diphosphate synthase

In a previous study, it was shown that the protein encoded by the gene B318L of African swine fever virus (ASFV) is a trans -prenyltransferase that catalyzes in vitro the condensation of farnesyl diphosphate and isopentenyl diphosphate to synthesize geranylgeranyl diphosphate and longer chain prenyl...

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Veröffentlicht in:	The Journal of biological chemistry 1999-06, Vol.274 (25), p.18033-18039
Hauptverfasser:	Alejo, A, Andres, G, Vinuela, E, Salas, M.L
Format:	Artikel
Sprache:	eng
Schlagworte:	African swine fever virus African Swine Fever Virus - enzymology African Swine Fever Virus - genetics alkyl (aryl) transferases Alkyl and Aryl Transferases - metabolism Animals biosynthesis cell lines cell membranes Chlorocebus aethiops Dimethylallyltranstransferase - genetics Dimethylallyltranstransferase - metabolism Diterpenes - analysis endoplasmic reticulum enzyme activity Farnesyltranstransferase immunocytochemistry infection isoprenoids Microscopy, Fluorescence Microscopy, Immunoelectron precursor viral membranes Sindbis Virus - enzymology Sindbis Virus - genetics Vero Cells Viral Proteins - metabolism
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