Recent progress in the total synthesis of naphthyridinomycin and lemonomycin tetrahydroisoquinoline antitumor antibiotics (TAAs)

In this tutorial review, which should be of general interest to synthetic organic chemists at large, recent progress in the total synthesis of the tetrahydroisoquinoline antitumor antibiotics cyanocycline A, naphthyridinomycin, bioxalomycin alpha2, and lemonomycin is highlighted in detail and some b...

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Veröffentlicht in:	Chemical Society reviews 2008-12, Vol.37 (12), p.2676-2690
Hauptverfasser:	Siengalewicz, Peter, Rinner, Uwe, Mulzer, Johann
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Antineoplastic Agents - chemical synthesis Antineoplastic Agents - chemistry Cell Line, Tumor Humans Hydroquinones - chemical synthesis Hydroquinones - chemistry Molecular Structure Naphthyridines - chemical synthesis Naphthyridines - chemistry Oxazoles - chemical synthesis Oxazoles - chemistry Tetrahydroisoquinolines - chemical synthesis Tetrahydroisoquinolines - chemistry Tetrahydroisoquinolines - pharmacology
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