Chloride permeation across the Deiters' neuron plasma membrane: activation by GABA on the membrane cytoplasmic side

Single plasma membranes were microdissected from Deiters' neurons freshly obtained from the lateral vestibular nucleus of the rabbit and their chloride permeability was studied in a microchamber system. The basal in→out 36Cl − permeation initially found was brought to zero by Zn 2+, 4,4′-diisot...

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Veröffentlicht in:	Neuroscience 1999, Vol.89 (4), p.1391-1400
Hauptverfasser:	Hydén, H, Cupello, A, Rapallino, M.V
Format:	Artikel
Sprache:	eng
Schlagworte:	4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid - pharmacology Animals Bicuculline - pharmacology Biological and medical sciences Biological Transport - drug effects Cell Membrane - drug effects Cell Membrane - physiology Central nervous system Chlorides - metabolism Cl − extrusion Deiters' neuron Electrophysiology Fundamental and applied biological sciences. Psychology GABA A receptors GABA-A Receptor Antagonists gamma-Aminobutyric Acid - pharmacology In Vitro Techniques intracellular GABA Iodides - pharmacology Kinetics Male Models, Neurological Neurons - drug effects Neurons - physiology Rabbits Receptors, GABA-A - physiology single membranes Vertebrates: nervous system and sense organs Vestibular Nucleus, Lateral - physiology Zinc - pharmacology
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