Identification of a Novel Gene Family Encoding Human Liver-specific Organic Anion Transporter LST-1

We have isolated a novel liver-specific organic anion transporter, LST-1, that is expressed exclusively in the human, rat, and mouse liver. LST-1 is a new gene family located between the organic anion transporter family and prostaglandin transporter. LST-1 transports taurocholate ( K m = 13.6 Î¼ m )...

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Veröffentlicht in:	The Journal of biological chemistry 1999-06, Vol.274 (24), p.17159-17163
Hauptverfasser:	Abe, T, Kakyo, M, Tokui, T, Nakagomi, R, Nishio, T, Nakai, D, Nomura, H, Unno, M, Suzuki, M, Naitoh, T, Matsuno, S, Yawo, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Anion Transport Proteins Arachidonic Acids - metabolism Biological Transport Carrier Proteins - genetics Carrier Proteins - metabolism Cations - metabolism DNA, Complementary - genetics Humans Liver - chemistry Liver - metabolism Mice Molecular Sequence Data Multigene Family Rats Recombinant Proteins - metabolism Sequence Analysis, DNA Sequence Homology, Amino Acid Steroids - metabolism Taurocholic Acid - metabolism Thyroid Hormones - metabolism
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