Increased Baroreflex Sensitivity and Reduced Cardiovascular Reactivity in Individuals with Chronic Low Blood Pressure
This study investigated aberrations in baroreflex function and cardiovascular reactivity related to the condition of chronic low blood pressure. In 40 hypotensive and 40 normotensive control subjects, blood pressures were continuously recorded at rest and during mental stress. Baroreflex sensitivity...
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| Veröffentlicht in: | Hypertension research 2008-10, Vol.31 (10), p.1873-1878 |
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| creator | Duschek, Stefan Dietel, Anja Schandry, Rainer Reyes Del Paso, Gustavo A |
| description | This study investigated aberrations in baroreflex function and cardiovascular reactivity related to the condition of chronic low blood pressure. In 40 hypotensive and 40 normotensive control subjects, blood pressures were continuously recorded at rest and during mental stress. Baroreflex sensitivity was determined in the time domain using sequence analysis. Beat-to-beat hemodynamic indices were estimated from the blood pressure waveforms by means of Modelflow analysis. In the hypotensive sample, a higher baroreflex sensitivity was observed under both conditions. Furthermore, this group experienced a less pronounced increase of blood pressure and stroke volume under stress. The findings underline the involvement of the baroreflex in the long-term setting of tonic blood pressure and suggest its relevance in the etiology of chronic hypotension. In addition, this study documents reduced cardiovascular reactivity and thus deficient hemodynamic adjustment to situational requirements in chronic low blood pressure. |
| doi_str_mv | 10.1291/hypres.31.1873 |
| format | Article |
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In 40 hypotensive and 40 normotensive control subjects, blood pressures were continuously recorded at rest and during mental stress. Baroreflex sensitivity was determined in the time domain using sequence analysis. Beat-to-beat hemodynamic indices were estimated from the blood pressure waveforms by means of Modelflow analysis. In the hypotensive sample, a higher baroreflex sensitivity was observed under both conditions. Furthermore, this group experienced a less pronounced increase of blood pressure and stroke volume under stress. The findings underline the involvement of the baroreflex in the long-term setting of tonic blood pressure and suggest its relevance in the etiology of chronic hypotension. In addition, this study documents reduced cardiovascular reactivity and thus deficient hemodynamic adjustment to situational requirements in chronic low blood pressure.</description><subject>Acute Disease</subject><subject>Adaptation, Physiological</subject><subject>Adult</subject><subject>Baroreflex - physiology</subject><subject>Blood Pressure - physiology</subject><subject>Cardiac Output - physiology</subject><subject>Chronic Disease</subject><subject>Female</subject><subject>Geriatrics/Gerontology</subject><subject>Health Promotion and Disease Prevention</subject><subject>Humans</subject><subject>Hypotension - physiopathology</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Obstetrics/Perinatology/Midwifery</subject><subject>original-article</subject><subject>Public Health</subject><subject>Stress, Psychological - physiopathology</subject><issn>0916-9636</issn><issn>1348-4214</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kDFv2zAQRomgQeK4WTsWnLrJ5okSJY2NkSYGDDRI2pmgyFPMQCZdUkzqf18GNpCpEw-8dx_uHiFfgC2g7GC5PewDxgWHBbQNPyMz4FVbVCVUn8iMdSCKTnBxSa5ifGGsbOsOLsgldAzquqtmJK2dDqgiGnqjgg84jPiXPqGLdrKvdjpQ5Qx9RJN0RlYqGOtfVdRpVCF_K32irKNrZ3JtkhojfbPTlq62wTur6ca_0ZvRe0Mf8q4xBfxMzoeM4fXpnZPfP25_re6Lzc-79er7ptBVKaZCDAPUojcMWNspobioB9E2FdOADTem4b1gSrTc9LxRfTUYNGKA0pQIzLQ9n5Nvx9x98H8SxknubNQ4jsqhT1GKrmUCgGdwcQR18DFmC3If7E6FgwQm30XLo2jJQb6LzgNfT8mp36H5wE9mM7A8AjG33DMG-eJTcPna_0X-A4_ajWQ</recordid><startdate>20081001</startdate><enddate>20081001</enddate><creator>Duschek, Stefan</creator><creator>Dietel, Anja</creator><creator>Schandry, Rainer</creator><creator>Reyes Del Paso, Gustavo A</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20081001</creationdate><title>Increased Baroreflex Sensitivity and Reduced Cardiovascular Reactivity in Individuals with Chronic Low Blood Pressure</title><author>Duschek, Stefan ; Dietel, Anja ; Schandry, Rainer ; Reyes Del Paso, Gustavo A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c426t-6ff156bd01089a6a365f68740c1e73dd73b60a683db37ab4fded6f12d2e10d8b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Acute Disease</topic><topic>Adaptation, Physiological</topic><topic>Adult</topic><topic>Baroreflex - physiology</topic><topic>Blood Pressure - physiology</topic><topic>Cardiac Output - physiology</topic><topic>Chronic Disease</topic><topic>Female</topic><topic>Geriatrics/Gerontology</topic><topic>Health Promotion and Disease Prevention</topic><topic>Humans</topic><topic>Hypotension - physiopathology</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Obstetrics/Perinatology/Midwifery</topic><topic>original-article</topic><topic>Public Health</topic><topic>Stress, Psychological - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Duschek, Stefan</creatorcontrib><creatorcontrib>Dietel, Anja</creatorcontrib><creatorcontrib>Schandry, Rainer</creatorcontrib><creatorcontrib>Reyes Del Paso, Gustavo A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Hypertension research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Duschek, Stefan</au><au>Dietel, Anja</au><au>Schandry, Rainer</au><au>Reyes Del Paso, Gustavo A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increased Baroreflex Sensitivity and Reduced Cardiovascular Reactivity in Individuals with Chronic Low Blood Pressure</atitle><jtitle>Hypertension research</jtitle><stitle>Hypertens Res</stitle><addtitle>Hypertens Res</addtitle><date>2008-10-01</date><risdate>2008</risdate><volume>31</volume><issue>10</issue><spage>1873</spage><epage>1878</epage><pages>1873-1878</pages><issn>0916-9636</issn><eissn>1348-4214</eissn><abstract>This study investigated aberrations in baroreflex function and cardiovascular reactivity related to the condition of chronic low blood pressure. 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| subjects | Acute Disease Adaptation, Physiological Adult Baroreflex - physiology Blood Pressure - physiology Cardiac Output - physiology Chronic Disease Female Geriatrics/Gerontology Health Promotion and Disease Prevention Humans Hypotension - physiopathology Internal Medicine Male Medicine Medicine & Public Health Obstetrics/Perinatology/Midwifery original-article Public Health Stress, Psychological - physiopathology |
| title | Increased Baroreflex Sensitivity and Reduced Cardiovascular Reactivity in Individuals with Chronic Low Blood Pressure |
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