Evidence for Cytokine Mediation of Disease Expression in Adults Experimentally Infected with Influenza A Virus

The roles of interleukin (IL)—6 and IL-8 in mediating the symptoms and signs of influenza A infection were examined. Adults were intranasally inoculated with a rimantadine-sensitive strain of influenza A HlNl virus and treated with rimantadine or placebo. Viral shedding, secretion weights, symptom s...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of infectious diseases 1999-07, Vol.180 (1), p.10-14
Hauptverfasser:	Skoner, David P., Gentile, Deborah A., Patel, Asha, Doyle, William J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Allergies Antiviral Agents - therapeutic use Biological and medical sciences Cytokines Experimental viral diseases and models Female Fundamental and applied biological sciences. Psychology Humans Infections Infectious diseases Influenza A virus Influenza A virus - drug effects Influenza, Human - drug therapy Influenza, Human - immunology Interleukin-6 - analysis Interleukin-8 - analysis Major Articles Male Medical sciences Microbiology Middle Aged Mucus - immunology Nasal Lavage Fluid - immunology Placebos Pretreatment Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains Rhinovirus Rimantadine Rimantadine - therapeutic use Secretion Statistics, Nonparametric Symptoms Viral diseases Virology Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!